Clinical Study of Comorbidities of Attention Deficit Hyperactivity in Children and Adolescents.

NCT04946877 | Unknown

• 1 other identifier: Comorbidities with ADHD
• Study Type: observational
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

Determine the frequency of psychiatric and neurological comorbidities in children and adolescence diagnosed with ADHD.

Conditions

Attention Deficit Hyperactivity Disorder

Keywords

ADHD,comorbidities

Outcome Measures

Primary Outcomes (1)

• Determine psychiatric comorbidities in children and adolescents with ADHD using Mini international neuropsychiatric interview for children and adolescents (M.I.N.I. Kid).

  Mini international neuropsychiatric interview for children and adolescents (M.I.N.I. Kid): is structured clinical diagnostic interview designed to assess the presence of current ICD-10 and DSM-IV psychiatric disorders in children and adolescents age 6-17 years

  baseline

Secondary Outcomes (1)

• determinate presence of soft neurological sign in children and adolescents with ADHD using Cambridge neurological inventory.

  baseline

Study Arms (2)

case group

100 ADHD patients; will be taken from outpatient clinic of child and adolescence psychiatry of Assiut university hospitals.

Diagnostic Test: IQ assessment using Wechsler intelligence scale for children third edition (WISC-III)

control group

100 normal children; they will be selected from neurology clinic complaining from minor neurological complaint e.g : headache, will match with the case group for age, sex and educational level.

Diagnostic Test: IQ assessment using Wechsler intelligence scale for children third edition (WISC-III)

Interventions

IQ assessment using Wechsler intelligence scale for children third edition (WISC-III) DIAGNOSTIC_TEST

IQ assessment using Wechsler intelligence scale for children third edition (WISC-III): is consists of several subtests, each classified into a verbal or performance scale .

Also known as: Mini international neuropsychiatric interview for children and adolescents (M.I.N.I. Kid), Child behavior checklist (CBCL), parent form, Neurological assessment using Cambridge neurological inventory

case group; control group

Eligibility Criteria

• Age: 6 Years - 17 Years
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

Case group will include 100 ADHD patients; will be taken from outpatient clinic of child and adolescence psychiatry of Assiut university hospitals. Control group will include 100 normal children; they will be selected from neurology clinic complaining from minor neurological complaint e.g : headache, will match with the case group for age, sex and educational level.

You may qualify if:

• Age: 6-17 years.
• Sex: both sexes will be included in the study.
• IQ≥70.

You may not qualify if:

• Age: less than 6 years or more than 17 years.
• IQ\<70.
• Patients with major neurological deficits, cerebral palsy and uncontrolled epilepsy.
• Patients with major psychiatric disorders e.g schizophrenia spectrum disorder.
• Patient who refusing to participate in the study or their caregiver refusing to give informed consent.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Gillberg C, Gillberg IC, Rasmussen P, Kadesjo B, Soderstrom H, Rastam M, Johnson M, Rothenberger A, Niklasson L. Co-existing disorders in ADHD -- implications for diagnosis and intervention. Eur Child Adolesc Psychiatry. 2004;13 Suppl 1:I80-92. doi: 10.1007/s00787-004-1008-4.

  PMID: 15322959 BACKGROUND

• Faraone SV, Asherson P, Banaschewski T, Biederman J, Buitelaar JK, Ramos-Quiroga JA, Rohde LA, Sonuga-Barke EJ, Tannock R, Franke B. Attention-deficit/hyperactivity disorder. Nat Rev Dis Primers. 2015 Aug 6;1:15020. doi: 10.1038/nrdp.2015.20.

  PMID: 27189265 BACKGROUND

• Jensen CM, Steinhausen HC. Comorbid mental disorders in children and adolescents with attention-deficit/hyperactivity disorder in a large nationwide study. Atten Defic Hyperact Disord. 2015 Mar;7(1):27-38. doi: 10.1007/s12402-014-0142-1. Epub 2014 Jun 19.

  PMID: 24942707 BACKGROUND

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders; Mental Disorders

Central Study Contacts

salma mohmed fahmi, msc

CONTACT

01067151755; saloma151@yahoo.com

Ahmed Abdelbaky Abd elrahman, MD

CONTACT

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: June 23, 2021
• First Posted: July 1, 2021
• Study Start: March 1, 2022
• Primary Completion: August 1, 2022
• Study Completion: October 1, 2022
• Last Updated: February 3, 2022

Record last verified: 2022-02