Willingness to Participate in Clinical Trials Among Black and African Americans

NCT04938895 | Completed

• 1 other identifier: IRB21-0864
• Study Type: interventional
• Target: 323
• Locations: 1 country
• Sites: 1

Brief Summary

Despite significant racial disparities in health outcomes, racial minority groups in the United States are not adequately represented in clinical trials, and clinical trial results published in major medical journals often underreport racial demographic data of participants. Lack of diversity in clinical trials threatens the generalizability of study results and reduces the ability of minority groups to benefit from medical advancement and innovation. Prior studies show that Black men are more likely to engage in preventive services when there is racial concordance with their healthcare provider. There is minimal literature about how racial concordance or diversity in clinical trial leadership impacts study enrollment. This project examines whether patients' willingness to participate in randomized clinical trials differs based on the characteristics of the investigator.

Conditions

Researcher-Subject Relations

Outcome Measures

Primary Outcomes (1)

• Willingness to Participate in a Clinical Trial

  Survey respondents' willingness to participate in a vaccine clinical trial led by the person in the photo.

  February 17, 2022 - February 19, 2022

Study Arms (4)

Black Woman Investigator

EXPERIMENTAL

Survey respondents are exposed to a Black woman investigator.

Behavioral: Black Respondents Exposure to a Photo

Black Man Investigator

EXPERIMENTAL

Survey respondents are exposed to a Black man investigator.

Behavioral: Black Respondents Exposure to a Photo

White Woman Investigator

EXPERIMENTAL

Survey respondents are exposed to a white woman investigator.

Behavioral: Black Respondents Exposure to a Photo

White Man Investigator

EXPERIMENTAL

Survey respondents are exposed to a white man investigator.

Behavioral: Black Respondents Exposure to a Photo

Interventions

Black Respondents Exposure to a Photo BEHAVIORAL

Black survey respondents will be randomly assigned to one of four treatments. In each treatment arm, the subject will view a photo of an NIH investigator. We experimentally vary treatment along two dimensions: whether the investigator is a man v. woman and whether the man is white vs. black. We will survey participants' willingness to participate in a clinical trial and how their initial response is impacted by other characteristics such as perceived trustworthiness and quality.

Black Man Investigator; Black Woman Investigator; White Man Investigator; White Woman Investigator

Eligibility Criteria

• Age: 25 Years - 64 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• participant identifies as Black or White

You may not qualify if:

• participant doesn't identify as Black or White
• younger than 25 years old, older than 64

Sponsors & Collaborators

• Harvard University: lead

Study Sites (1)

Harvard University

Cambridge, Massachusetts, 02138, United States

Location

Study Officials

• Marcella Alsan, MD,PhD

  Harvard University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Public Policy

Study Record Dates

• First Submitted: June 22, 2021
• First Posted: June 24, 2021
• Study Start: June 7, 2021
• Primary Completion: February 21, 2022
• Study Completion: February 21, 2022
• Last Updated: May 19, 2023

Record last verified: 2023-05

Locations

US (1)