NCT04936932

Brief Summary

Laser treatment of Basal cell carcinoma

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 21, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 23, 2021

Completed
4 months until next milestone

Study Start

First participant enrolled

November 1, 2021

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 20, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 20, 2022

Completed
Last Updated

December 8, 2022

Status Verified

December 1, 2022

Enrollment Period

10 months

First QC Date

June 21, 2021

Last Update Submit

December 6, 2022

Conditions

Keywords

Superficial Basal Cell Carcinoma

Outcome Measures

Primary Outcomes (1)

  • Complete clearance of BCC

    Histological confirmation of BCC clearance. Biopsy will be taken from the treatment site to confirm complete BCC clearance

    1 year

Secondary Outcomes (1)

  • Cosmetic outcome

    1 year

Study Arms (2)

Standard

ACTIVE COMPARATOR

1064 Long-pulse Nd:YAG laser Fluence: 120 J/cm2 Number of passes: Single Spot size: 2 cm Pulse width: 8-10 msec

Device: 1064 nm long-pulse Nd:YAG laser

Slow

ACTIVE COMPARATOR

1064 Long-pulse Nd:YAG laser Fluence: 20-30 J/cm2 Number of passes: Multiple Spot size: 2 cm Pulse width: 8-10 msec

Device: 1064 nm long-pulse Nd:YAG laser

Interventions

BCC lesion will be treated with long-pulse 1064 laser

Standard

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthy subjects 18 years of age or older
  • Lesion is biopsy-proven superficial BCC \<= 2.0 cm in largest diameter
  • BCC is on trunk or extremities
  • Seeks and is scheduled for treatment of BCC
  • Willing to have photographs taken of the treatment area
  • Ability to understand and the willingness to sign a written informed consent document
  • Agrees to adhere to the treatment and follow-up schedule and post treatment care instructions

You may not qualify if:

  • Subjects with a BCC lesion that requires excision. This would include relatively larger lesions (\>2.0 cm in diameter), high risk lesions as defined by American Academy of Dermatology as recurrent and sclerosing subtype BCC, or metastases.
  • Pregnancy
  • Subjects unable to follow-up for the full 12-months
  • Subjects not willing to have biopsy taken from the treatment area
  • Subjects with herpes simplex virus infection, impetigo or other disqualifying condition as determined by a dermatologist on the treatment area or effecting healing or outcome

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Skin & Allergy Center

Spring Hill, Tennessee, 37174, United States

Location

MeSH Terms

Conditions

Carcinoma, Basal Cell

Condition Hierarchy (Ancestors)

CarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsNeoplasms, Basal Cell

Study Officials

  • Chris Robb, MD

    Skin & Allergy Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 21, 2021

First Posted

June 23, 2021

Study Start

November 1, 2021

Primary Completion

August 20, 2022

Study Completion

August 20, 2022

Last Updated

December 8, 2022

Record last verified: 2022-12

Data Sharing

IPD Sharing
Will not share

Locations