Remineralization of Dentine Caries Using Two Remineralizing Agents Which Are Nanosilver Fluoride and Casein phosphopeptides_amorphous Calcium Phosphate
1 other identifier
interventional
135
1 country
1
Brief Summary
The study is randomized controlled trial ...The null hypothesis suggests that there is no significant difference between nanosilver fluoride and sodium fluoride with Casein phosphopeptides\_amorphous calcium phosphate in the remineralization of dental caries.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Aug 2021
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 31, 2021
CompletedFirst Posted
Study publicly available on registry
June 18, 2021
CompletedStudy Start
First participant enrolled
August 10, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 20, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 20, 2022
CompletedMay 17, 2022
May 1, 2022
1 month
May 31, 2021
May 16, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The incidence of patient with arrested dental caries using international caries detection and assessment system II(ICDAS II)
The measure will be done using international caries detection and assessment system II (ICDAS II) criteria for diagnosing active and arrested caries by blunt probe.
Change in the state of dental caries after one and 3 months after topical application of nanosilver fluoride and sodium fluoride with casein phosphopeptides amorphous calcium phosphate
Study Arms (3)
Nanosilver fluoride group
EXPERIMENTALNanosilver fluoride will be applied on carious lesion
Sodium fluoride with casein phosphopeptides_Amorphous calcium phosphate group
ACTIVE COMPARATORSodium fluoride with casein phosphopeptides\_Amorphous calcium phosphate will be applied on carios lesion
Sodium fluoride varnish group
ACTIVE COMPARATORSodium fluoride varnish will be applied on carios lesion
Interventions
Nanosilver fluoride will be applied to the affected tooth in single application and then follow up after one and three months
Sodium fluoride with casein phosphopeptides amorphous calcium phosphatewill be applied to the affected tooth in single application and then follow up after one and three months
Sodium fluoride varnish will be applied to the affected tooth in single application and then follow up after one and three months
Eligibility Criteria
You may not qualify if:
- sensitivity to Silver or other heavy-metal ions or any milk-related allergies and medical conditions involving the kidneys.
- The tooth was excluded if it had pulp exposure, abscess/fistula, sensitivity to percussion
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Alhur alriyahi specialized dental center
Karbala, Iraq
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Duaa Jawad
University of Baghdad
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dentist.. master student
Study Record Dates
First Submitted
May 31, 2021
First Posted
June 18, 2021
Study Start
August 10, 2021
Primary Completion
September 20, 2021
Study Completion
June 20, 2022
Last Updated
May 17, 2022
Record last verified: 2022-05