NCT04928326

Brief Summary

This is an observational study to evaluate the agreement between the InCardia diagnostic technology CorWatch for the assessment of venous pressure in human subjects. This includes evaluation of InCardia technology in heart failure (HF) patients undergoing invasive right heart catheterization in a cardiac catheterization laboratory (cath lab) and in a cardiac intensive care unit (ICU).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
43

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Aug 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 8, 2021

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 16, 2021

Completed
2 months until next milestone

Study Start

First participant enrolled

August 1, 2021

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2022

Completed
Last Updated

March 6, 2024

Status Verified

March 1, 2024

Enrollment Period

1.1 years

First QC Date

June 8, 2021

Last Update Submit

March 4, 2024

Conditions

Keywords

central venous pressureright heart catheterizationhemodynamic congestion

Outcome Measures

Primary Outcomes (1)

  • Agreement with right atrial pressure as measured by Swan Ganz catheter

    Agreement between the CVP/RAP as assessed by the CorWatchTM method and the right arterial pressure (RAP) as measured by SG catheter

    During the right heart catheterization procedure

Study Arms (1)

Patients with heart failure undergoing right heart catheterization

Subjects with a diagnosis of NYHA class II-IV heart failure who meet the inclusion and exclusion criteria will be eligible for participation in this study.

Diagnostic Test: CorWatch

Interventions

CorWatchDIAGNOSTIC_TEST

Non-invasive wearable monitor for the assessment of central venous pressure

Patients with heart failure undergoing right heart catheterization

Eligibility Criteria

Age21 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subjects with a diagnosis of NYHA class II-IV heart failure who meet the inclusion and exclusion criteria will be eligible for participation in this study.

You may qualify if:

  • Diagnosed with NYHA class II-IV heart failure irrespective of ejection fraction
  • Patient is able to give consent

You may not qualify if:

  • Severe tricuspid regurgitation
  • Mechanical ventilation
  • Patient is pregnant
  • Inability to access either of the patient's upper arms.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of California San Francisco

San Francisco, California, 94143, United States

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 8, 2021

First Posted

June 16, 2021

Study Start

August 1, 2021

Primary Completion

September 1, 2022

Study Completion

October 1, 2022

Last Updated

March 6, 2024

Record last verified: 2024-03

Data Sharing

IPD Sharing
Will not share

Locations