Medical Treatment of Solid Tumors at the Lyon University Hospital Cancer Institute During the First Wave of COVID-19 in France: A Conservative Approach

NCT04910633 | Completed

• 1 other identifier: 69HCL21_0005
• Study Type: observational
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

An article to present how cancer patients were taken in charge at Lyon University Hospital Cancer Institute (France) during the first peak of the COVID-19 pandemic between March and May 2020 is under writing. It will present strategies that were set-up to avoid cross-contamination between patients and caregivers, patients treatment adaptation (timing, dosage,..) and how consultations, multidisciplinary team meetings, surgical procedures and clinical trials were impacted. Part of this article will also illustrate the characteristics of patients with a solid tumor(s) that have been hospitalized during this timeframe for the COVID-19. How cancer type and stage affect Covid severity and mortality.will be described for a small sample of patients (44). These qualitative figures will be compared to literature current state of the art.

Conditions

Cancer; Solid Tumor; Covid19

Keywords

COVID-19; Cancer; Solid Tumor; Qualitative study; First pandemic wave

Outcome Measures

Primary Outcomes (1)

• Illustration of the repartition of COVID+ patient severity (Low/Medium/Severe status) depending on cancer nature, stage and patient age.

  COVID-19 severity will be determined based on chest X-Ray damage as follow. Low severity : ≤25% of chest X-Ray damage, Middle severity: between 25-50% of chest X-Ray damage, High Severity : above 50% of chest X-Ray damage. A graphic will then be drafted to present the relationship between Covid-19 severity depending on patient age, cancer nature, and cancer stage.

  At the end of Month 1

Study Arms (1)

Solid Tumor and COVID-19

Patients with a solid tumor followed by an oncologist of Lyon University Hospital Cancer Institute (LUHCI) who have been hospitalized at LUHCI for the COVID-19 between March and May 2020 and who didn't oppose the reuse of their medical file data for research purpose.

Other: COCA is an observational study based on retrospective data issued from patient medial file.

Interventions

COCA is an observational study based on retrospective data issued from patient medial file. OTHER

The following parameters will be collected from the medical files of the patients involved in this study: * Age * Gender * Cancer type * Cancer Stage * Cancer Treatment * COVID-19 severity (based on chest X-Ray damage. Low ≤25%, Middle: between 25-50%, High above 50%) * Living Status * Attribution of Mortality to COVID status * Comorbidities

Solid Tumor and COVID-19

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with a LUHCI cancer code created after 2015 and a LUHCI COVID-19 code created between March 2020 and May 2020.

You may qualify if:

• Patients with a LUHCI code created after 2015 and a LUHCI COVID-19 code created between March 2020 and May 2020.

You may not qualify if:

• Patients who did not allow the reuse of their medical file data for research related to COVID-19-

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Lyon University Hospital Cancer Institute

Bron, 69 677, France

Location

MeSH Terms

Conditions

Neoplasms; COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 10, 2021
• First Posted: June 2, 2021
• Study Start: December 2, 2020
• Primary Completion: December 9, 2020
• Study Completion: January 22, 2021
• Last Updated: June 2, 2021

Record last verified: 2021-05

Locations

FR (1)