NCT04909983

Brief Summary

A feasibility study of treatment with a occlusive medical device or patch in pediatric patients with type 1 diabetes suffering from irritative contact dermatitis due to diabetes devices.

Trial Health

57
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
17

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2021

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 19, 2021

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

May 20, 2021

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 2, 2021

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2022

Completed
Last Updated

November 22, 2022

Status Verified

November 1, 2022

Enrollment Period

1.4 years

First QC Date

May 20, 2021

Last Update Submit

November 17, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Response rate of active treatment versus standard of care

    8 days after active treatment compared to 8 days after standard of care

Secondary Outcomes (1)

  • Time to resolution of Irritative contact dermatitis

    After 8 days

Study Arms (2)

Intervention

EXPERIMENTAL

Medical Device, an occlusive patch for 3 days.

Device: DPLX-PT1

Control

ACTIVE COMPARATOR

Standard of Care

Other: Control arm

Interventions

DPLX-PT1DEVICE

A polymer skin patch for occlusional therapy

Intervention

Standard of care

Control

Eligibility Criteria

Age6 Years - 20 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Signed informed consent, and for patients under the legal age consent by a legal guardian
  • Clinically confirmed, active and evaluable irritant contact dermatitis (ICD)
  • Age 6-20 at the time of signing the informed consent form (ICF)
  • Ability to answer study questionnaires

You may not qualify if:

  • Any type of skin irritation other than ICD
  • Use of occlusive therapy for the treatment of their ICD, or unwilling to refrain from this treatment for duration of study
  • For any other reason considered unsuitable by the investigator
  • Pregnant or of child-bearing potential unwilling to use acceptable effective contraception

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pediatric Department, Herlev Hospital

Herlev, 2730, Denmark

Location

MeSH Terms

Conditions

Dermatitis, IrritantDiabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Dermatitis, ContactDermatitisSkin DiseasesSkin and Connective Tissue DiseasesSkin Diseases, EczematousDiabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Anna Korsgaard Berg, MD

    Pediatric Department, Herlev Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator MD

Study Record Dates

First Submitted

May 20, 2021

First Posted

June 2, 2021

Study Start

May 19, 2021

Primary Completion

October 1, 2022

Study Completion

October 1, 2022

Last Updated

November 22, 2022

Record last verified: 2022-11

Data Sharing

IPD Sharing
Will not share

Locations