NCT04899609

Brief Summary

Social interactions are part of our daily lives. Communicating with others is a recurring choice which is based on emotional cues, such as facial expression. Our action must be adapted to the emotional state of our interlocutor, otherwise the investigators will have poor quality interactions An emotional stimulus would cause a conditioned response (innate reaction). Thus, the presence of an angry person would automatically trigger flight behavior. More recently, however, it has been envisioned that this same avoidance behavior could be the result of a goal-directed behvior. In this case, the avoidance behavior would be the result of an evaluation of the consequences of the selected action. These goal-directed behaviors are guided by a mental representation of consequences The project aims to study behavioral choices (approach and avoidance) in response to negative and positive social cues (anger and joy) in 40 healthy volunteers using a computerized neuropsychological task, and to determine wheter these choices are the result of goal-directed behavior. The study also aims to assess the modulation of behavioral adaptation by the level of impulsivity, lonilness, empathy, and by the capcity to understand others' intenstions.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 18, 2021

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 24, 2021

Completed
8 days until next milestone

Study Start

First participant enrolled

June 1, 2021

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2022

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2022

Completed
Last Updated

September 8, 2021

Status Verified

September 1, 2021

Enrollment Period

1 year

First QC Date

May 18, 2021

Last Update Submit

September 6, 2021

Conditions

Keywords

EmotionMotivationDecision makingGoal-director behavior

Outcome Measures

Primary Outcomes (1)

  • Percentage of approach and avoidance behavior in response to positive (joy) and negative (anger) social signals

    Calculation of the proportion of avoidance vs. approach choices

    1 day

Secondary Outcomes (1)

  • Response time

    1 day

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Healthy volunteers

You may qualify if:

  • Being between 18 and 65 years old
  • Absence of psychiatric pathology over the entire life
  • Being able to understand the nature, purpose and methodology of the study

You may not qualify if:

  • Mental retardation or sever medical co-morbidity
  • Sensory or cognitive disability
  • Pregnant or breastfeeding woman
  • Protection by law (guardianship or curatorship)
  • Deprivation of liberty (by judicial or administrative decision)
  • Inability to understand, speak and write French

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University hospital

Montpellier, 34295, France

RECRUITING

Study Officials

  • Emilie Olie, MD PhD

    University Hospital, Montpellier

    STUDY DIRECTOR

Central Study Contacts

Nathan RISCH, MD (intern)

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 18, 2021

First Posted

May 24, 2021

Study Start

June 1, 2021

Primary Completion

June 1, 2022

Study Completion

December 30, 2022

Last Updated

September 8, 2021

Record last verified: 2021-09

Locations