NCT04897230

Brief Summary

Introduction: Yoga has been shown to reduce stress and have benefits for a number of stress-related disorders. However, the effects of an acute bout of yoga practice on cardiac autonomic response to and recovery from stress remain unclear. This study aimed to examine the effect of a single bout of yoga on heart rate (HR) and heart rate variability (HRV) response to and recovery from mental stress. Materials and Methods: This study was conducted with a randomized, counterbalanced, crossover design. A total of 44 participants completed two sessions (yoga and video watching (VW)) in randomly assigned order. After each condition, participants underwent a Stroop task and mental arithmetic task. Electrocardiogram was measured and HR and HRV for resting, each condition, and the stress and recovery periods were analyzed.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2013

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2013

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 30, 2015

Completed
6.1 years until next milestone

First Submitted

Initial submission to the registry

May 12, 2021

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 21, 2021

Completed
Last Updated

May 21, 2021

Status Verified

May 1, 2021

Enrollment Period

1.6 years

First QC Date

May 12, 2021

Last Update Submit

May 20, 2021

Conditions

Keywords

yoga, mental stress, cardiac autonomic function, stress response

Outcome Measures

Primary Outcomes (2)

  • Heart Rate

    Heart rate was derived from continuous heart rate recording, at a sampling rate of 1024 Hz, using an electrocardiogram (ECG) system

    up to 5 minutes

  • Heart Rate Variability

    Heart rate variability was derived from continuous heart rate recording, at a sampling rate of 1024 Hz, using an electrocardiogram (ECG) system

    up to 5 minutes

Study Arms (2)

Hatha Yoga Condition

ACTIVE COMPARATOR

An experienced yoga instructor led the 30 minutes yoga condition session which consisted of 5 minutes warm up, 5 minutes breathing exercises, and 20 minutes yoga poses practice. The yoga props were used according to each participant's particular body type and needs to help he/she achieve precise yoga postures safely and comfortably.

Behavioral: Hatha Yoga

Control Condition

PLACEBO COMPARATOR

Participants in the control condition were watching a neutral video on a television.

Behavioral: Video Watching

Interventions

Hatha YogaBEHAVIORAL

The yoga poses were chosen for providing a restorative session based on their purported relationship to restorative effects to best promote cardiac autonomic recovery from mental stress.

Hatha Yoga Condition
Video WatchingBEHAVIORAL

The video was about the history of the Earth which encompasses the development of the planet Earth from its formation to the present day.

Control Condition

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • aged between 20 and 40 years old
  • a body mass index (BMI) between 18.5 and 30
  • being sedentary

You may not qualify if:

  • Electrocardiogram (ECG) abnormalities (e.g., arrhythmia, atrioventricular blocks)
  • history of cardiovascular disease, diabetes, or renal disease
  • contraindications for exercise (e.g., orthopedic problems)
  • involvement in any yoga practice
  • being pregnant or nursing
  • use of tobacco products or medications that may affect cardiovascular function

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Stress, PsychologicalFractures, Stress

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorFractures, BoneWounds and Injuries

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 12, 2021

First Posted

May 21, 2021

Study Start

September 1, 2013

Primary Completion

March 30, 2015

Study Completion

March 30, 2015

Last Updated

May 21, 2021

Record last verified: 2021-05

Data Sharing

IPD Sharing
Will not share