NCT04893824

Brief Summary

Ambispective, multi-surgeon, single site, consecutive case series to determine the safety, performance, and benefits of the Grappler(R) Interference Screw.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 19, 2021

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

May 11, 2021

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 20, 2021

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 11, 2022

Completed
14 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 25, 2022

Completed
Last Updated

November 15, 2023

Status Verified

March 1, 2022

Enrollment Period

11 months

First QC Date

May 11, 2021

Last Update Submit

November 14, 2023

Conditions

Outcome Measures

Primary Outcomes (3)

  • Incidence of revisions

    Safety will be assessed by recording the incidence of revisions. The relationship of events will be attributed to either the implant or instrumentation.

    6 Months Post-Op

  • Incidence of adverse events

    Safety will be assessed by recording the incidence of adverse events. The relationship of events will be attributed to either the implant or instrumentation.

    6 Months Post-Op

  • Incidence of complications

    Safety will be assessed by recording the incidence of complications. The relationship of events will be attributed to either the implant or instrumentation.

    6 Months Post-Op

Secondary Outcomes (7)

  • Rate of recurrence of deformity

    7 Weeks Post-Op, 6 Months Post-Op

  • Rate of implant failure

    Intra-Op, 7 Weeks Post-Op, 6 Months Post-Op

  • Rate of re-tear or re-rupture of fixated soft tissue

    7 Weeks Post-Op, 6 Months Post-Op

  • Rate of screw removal

    7 Weeks Post-Op, 6 Months Post-Op

  • Foot and Ankle Mobility Measure

    6 months post-operative

  • +2 more secondary outcomes

Interventions

Foot and/or ankle procedure involving soft tissue attachment to bone using the Grappler® Interference Screw System

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The investigational population will include a minimum of 50 subjects who have undergone a foot and/or ankle procedure that fulfill the eligibility criteria

You may qualify if:

  • The subject must have undergone a foot and/or ankle procedure involving soft tissue attachment to bone using the Grappler® Interference Screw System and completed by one of the designated investigators who are experienced in the use of such implants and the required specialized surgical techniques
  • The subject must have adequate radiographic and medical records for the minimum follow-up requirement of six months
  • For the Prospective Data Collection:
  • \- The subject is willing to provide written informed consent

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Orthopedic Foot and Ankle

Worthington, Ohio, 43085, United States

Location

MeSH Terms

Conditions

Ankle Injuries

Condition Hierarchy (Ancestors)

Leg InjuriesWounds and Injuries

Study Officials

  • Jacy Legue

    Paragon 28

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
OTHER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 11, 2021

First Posted

May 20, 2021

Study Start

April 19, 2021

Primary Completion

March 11, 2022

Study Completion

March 25, 2022

Last Updated

November 15, 2023

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations