Impact of SARS-CoV-2 (COVID-19) Infection, Treated in Ambulatory Care, on Long-term Quality of Life in a Parisian Military Population

NCT04893070 | Completed

• 2 other identifiers: 2020-COVID19-382021-A01038-33
• Study Type: observational
• Target: 173
• Locations: 1 country
• Sites: 1

Brief Summary

In April 2020, a meta-analysis on the long-term sequelae of respiratory syndromes related to seasonal coronaviruses (SARS and MERS) showed a significant alteration in quality of life, with in particular a decrease in physical and emotional capacities and a deterioration of social life. An improvement of the quality of life is evidenced after 6 months but without reaching the level usually observed in healthy people. The impact of SARS-CoV-2 infection on quality of life can be explained by the persistence of pleomorphic symptoms in the medium to long term. In the military population, the majority of SARS-CoV-2 cases present minor to moderate forms of the disease. Military personnel have living conditions that differ from those of the general population, in particular because of their geographic mobility, which may be responsible for isolation from the family. This isolation can be regular (we speak of "geographical celibacy" when the soldier is posted in a geographical area far from the family unit) and/or occasional, during missions on the national territory or outside. This singularity justifies a study on the impact of SARS-CoV-2 (COVID-19) infection on the quality of life in this specific population.

Conditions

SARS-CoV2 Infection; Covid19

Keywords

Quality of life

Outcome Measures

Primary Outcomes (1)

• Long-term quality of life (mental component)

  Mental Component Score (MCS) of the SF-36 questionnaire. The MCS ranges from 0 (bad quality of life) to 100 (good quality of life).

  18 months after COVID-19 first symptoms

Secondary Outcomes (1)

• Long-term quality of life (physical component)

  18 months after COVID-19 first symptoms

Study Arms (2)

COVID+

Questionnaires on COVID-19 symptomatology and quality of life

Other: Questionnaires COVID+

COVID-

Questionnaires on quality of life

Other: Questionnaires COVID-

Interventions

Questionnaires COVID- OTHER

* 1 questionnaire on quality of life at enrollment * 1 questionnaire on quality of life 6 months after enrollment

COVID-

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population is composed of military staff followed at the 1st Centre Médical des Armées (Paris, France) who have suffered from COVID-19 and were managed in ambulatory care (COVID+ group) and who have not been infected by SARS-CoV-2 (COVID- group).

You may qualify if:

• Military personnel
• COVID+: diagnosed with COVID-19 and managed in ambulatory care since March 14th, 2020
• COVID-: not having been infected with SARS-CoV-2

You may not qualify if:

• Hospitalized for COVID-19
• Having received a treatment against COVID-19 (other than paracetamol)

Sponsors & Collaborators

• Direction Centrale du Service de Santé des Armées: lead

Study Sites (1)

1er Centre Médical des Armées

Paris, 75012, France

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 11, 2021
• First Posted: May 19, 2021
• Study Start: July 15, 2021
• Primary Completion: July 4, 2022
• Study Completion: July 4, 2022
• Last Updated: October 17, 2022

Record last verified: 2022-10

Locations

FR (1)