Identification Of Occupational Exposures In Patients With ILD

NCT04879082 | Completed

• 1 other identifier: A257
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

Diffuse interstitial lung disease brings together a heterogeneous group of pulmonary pathologies, characterized by infiltrating and diffuse lesions of the pulmonary interstitium. The evolving risk of these ILD is pulmonary fibrosis, with the development of chronic respiratory failure. The process of the etiological diagnosis of ILD results from a multidisciplinary approach (pulmonologists, radiologists, occupational health specialists, anatomo-pathologists, etc…). Indeed, the multitude of possible causes of these diseases makes the etiological diagnosis difficult. Professional aetiologies are also frequently mentioned : pneumoconiosis, hypersensitivity pneumonitis, as a differential diagnosis. It therefore appears essential to deepen the professional aspect during the diagnostic process for ILD. Since May 2020, a professional interview has been systematically offered by the Occupational Pathology Consultation Center of the Hospital Center Lyon Sud, to patients followed by the team of Professor Vincent COTTIN, whose file was discussed in a multidisciplinary meeting. The data collected to constitute a database are the following variables: age, sex, diploma, professional course coded in CITP (International Standard Classification of Professions) and NAF (French Nomenclature of Activities), occupational exposures, smoking, risk factors non-professionals, clinical elements of ILD and elements relating to an occupational disease certificate. This database is anonymized.

Conditions

Occupational Exposure; Interstitial Lung Disease

Keywords

Occupational Exposure; Lung Fibrosis; Interstitial Lung Disease; Pulmonary Fibrosis

Outcome Measures

Primary Outcomes (2)

• Study the distribution of occupational exposures according to the types of ILD. The precise diagnosis is retained during the multidisiciplinary meeting.

  Precise diagnosis of ILD : type of PID diagnosed

  The precise diagnosis of ILD is retained immediately after the multidisiciplinary meeting.

• Occupational exposures are assessed in specialized consultation by the occupational physician.

  Occupational exposures

  Occupational exposures are assessed immediately after the occupational consultation.

Study Arms (1)

ILD

Patients with ILD, whose file has been discussed in a multidisciplinary meeting since May 2020 at the Louis Pradel Pneumological Hospital, and who have benefited from a professional interview in the Occupational pathology consultation center of the Hospital Center Lyon Sud.

Other: Professional course, occupational exposures

Interventions

Professional course, occupational exposures OTHER

The data collected are the following variables: age, sex, diploma, professional course coded in CITP (International Standard Classification of Professions) and NAF (French Nomenclature of Activities), occupational exposures, smoking, risk factors non-professionals, clinical elements of ILD and elements relating to an occupational disease certificate. This database is anonymized. The precise diagnosis of ILD is retained during the multidisiciplinary meeting. Occupational exposures are assessed in specialized consultation : * a first professional interview phase: The professional history is traced, listing the training courses followed and the trades carried out. The questioning is precise and focuses on the different tasks performed, and the products used. * a second step, where a questionnaire is completed by the doctor: A list of specific substances is offered to the patient, who responds whether or not he thinks he has been exposed to them in his professional past.

ILD

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with ILD

You may qualify if:

• Patients with ILD.
• File discussed in a multidisciplinary meeting since May 2020 at the Louis Pradel Pneumological Hospital.
• Have benefited from a professional interview in the Occupational pathology consultation center of the Hospital Center Lyon Sud.

You may not qualify if:

• Patients with sarcoidosis.

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Centre de consultation de pathologie professionnelle, Centre Hospitalier Lyon Sud

Pierre-Bénite, 69310, France

Location

MeSH Terms

Conditions

Lung Diseases, Interstitial; Pulmonary Fibrosis

Interventions

Occupational Exposure

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Fibrosis; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Environmental Exposure; Environmental Pollution; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 26, 2021
• First Posted: May 10, 2021
• Study Start: May 15, 2020
• Primary Completion: March 15, 2021
• Study Completion: April 15, 2021
• Last Updated: May 10, 2021

Record last verified: 2021-03

Locations

FR (1)