NCT04869384

Brief Summary

Effect of Electronic Monitoring and Feedback on Adherence to Easyhaler Controller Medication in Patients with Asthma

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
158

participants targeted

Target at P50-P75 for phase_4 asthma

Timeline
Completed

Started Jun 2021

Typical duration for phase_4 asthma

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 27, 2021

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 3, 2021

Completed
2 months until next milestone

Study Start

First participant enrolled

June 23, 2021

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 24, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 24, 2024

Completed
Last Updated

November 4, 2024

Status Verified

October 1, 2024

Enrollment Period

2.8 years

First QC Date

April 27, 2021

Last Update Submit

October 31, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Mean weekly adherence to controller medication

    Adherence (percentage of doses taken of the doses prescribed) to controller medication during last six weeks of study

    Weekly during each of the last 6 weeks of treatment

Study Arms (2)

Intervention

EXPERIMENTAL

Subjects will receive reminders and feedback to improve their adherence via a sensor attached to Easyhaler inhaler and mobile application

Other: Reminders and feedback to improve adherence

Usual care

ACTIVE COMPARATOR

Subjects do not receive reminders and feedback, but receive treatment as usual.

Other: No reminders and feedback to improve adherence

Interventions

Subjects will receive reminders and feedback to improve their adherence.

Intervention

Subjects will not receive reminders and feedback to improve their adherence.

Usual care

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • written informed consent
  • male and female subjects with documented diagnosis of asthma
  • age 18 to 65 years
  • ACT score 19 or less at screening
  • treatment wih oral corticosteroids or hospital or emergency department admission due to asthma exacerbation within the past year
  • subject's able to use Easyhaler inhalers and comply with study requirements

You may not qualify if:

  • recent (within 1 month) asthma exacerbation
  • concomitant major respiratory disease which may complicate the measurement of asthma control
  • \>20 pack-year history of smoking
  • recent upper or lower respiratory tract infection
  • pregnant or lactating female subjects

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

MECS Research GmbH

Berlin, Germany

Location

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • Orion Corporation Clinical Study Director

    Orion Corporation, Orion Pharma

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 27, 2021

First Posted

May 3, 2021

Study Start

June 23, 2021

Primary Completion

April 24, 2024

Study Completion

April 24, 2024

Last Updated

November 4, 2024

Record last verified: 2024-10

Data Sharing

IPD Sharing
Will not share

Locations