NCT04860895

Brief Summary

The aim of this research is to use the Multi-Spectral method to measure the biomolecular fingerprint of the virus directly instead of the virus's RNA (RT-PCR) or the body's immune response (antibody) measurement methods to diagnose the SARS-COV-2 virus, thereby determining whether COVID-19 can be diagnosed faster, cheaper and without requiring a medical laboratory environment.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
4,400

participants targeted

Target at P75+ for not_applicable covid19

Timeline
Completed

Started Feb 2021

Shorter than P25 for not_applicable covid19

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 11, 2021

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

April 25, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 27, 2021

Completed
4 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2021

Completed
14 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 15, 2021

Completed
Last Updated

May 6, 2021

Status Verified

May 1, 2021

Enrollment Period

3 months

First QC Date

April 25, 2021

Last Update Submit

May 2, 2021

Conditions

Keywords

Artificial Intelligence, AI, SARS-COV2, Point of Care,

Outcome Measures

Primary Outcomes (2)

  • Assessment of AI's Learning Performance:

    Compared PCR results with AP-23 results; PCR Accordance, PCR Accordance for Negative Samples, PCR Accordance for Positive Samples.

    2 MONTHS

  • Evaluation of Artificial Intelligence's Test Performance)

    As a result of comparison with the PCR and AP-23 results in nasopharyngeal swab samples; Sensitiviy, Specificity, Negative Prediction Value, Positive Prediction Value

    1 MONTH

Study Arms (1)

Nasopharyngeal swabs

OTHER

Nasopharyngeal swabs samples of volunteers who is referred with suspicion of Covid19.

Diagnostic Test: AP-23

Interventions

AP-23DIAGNOSTIC_TEST

AP-23 newly developed point of care system as a well-automated combination of multi-spectral technology and a distributed cloud computing A.I. system which has been developed to detect COVID-19.

Nasopharyngeal swabs

Eligibility Criteria

Age12 Years - 95 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • All people who applied to hospitals with suspicion of COVID-19

You may not qualify if:

  • Person who cannot give nasopharyngeal samples

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sancaktepe Şehit Prof.Dr. İlhan Varank Training and Research Hospital

Sancaktepe, Istanbul, 34785, Turkey (Türkiye)

RECRUITING

Related Publications (1)

  • Tayfur I, Bayramoglu B, Guven R, Avci A. Diagnostic accuracy of artificial intelligence-based multi-spectrum analysis for molecular fingerprint detection of SARS-CoV-2. Medicine (Baltimore). 2025 May 23;104(21):e41928. doi: 10.1097/MD.0000000000041928.

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Officials

  • İsmail Tayfur, MD

    Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 25, 2021

First Posted

April 27, 2021

Study Start

February 11, 2021

Primary Completion

May 1, 2021

Study Completion

May 15, 2021

Last Updated

May 6, 2021

Record last verified: 2021-05

Locations