Radial Tunnel Syndrome in Resistant Lateral Epicondylitis

NCT04856228 | Completed

• 1 other identifier: E-83045809-604.01.02-7933
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

Lateral elbow pain can be difficult to diagnose because of the different pathologies or combinations of pathologies that can cause this clinic. Although lateral epicondylitis is the most common cause of lateral elbow pain, symptoms of radial tunnel syndrome may masquerade as lateral epicondylitis or they can be seen together with rate of 21-41%. The aim of the study is; to evaluate the presence of radial tunnel syndrome in the patients who have resistant lateral epicondylitis.

Conditions

Radial Tunnel Syndrome; Lateral Epicondylitis; Radial Nerve Compression; Epicondylitis of the Elbow

Keywords

radial nerve; radial tunnel syndrome; lateral epicondylitis; ultrasonography; electrophysiology

Outcome Measures

Primary Outcomes (1)

• Change from Baseline Pain via Nurmerical Rating Scale at 30 Minutes after PIN/Lateral Epicondyle Injection

  Pain of the participants will be assessed by one of the most commonly used pain scale "numerical rating scale". It is numeric version of visual analog scale in which a patient selects a whole number (0-10 integers) that best reflects the intensity of his/her pain. The 11-point numeric scale ranges from '0' representing "no pain" to '10' representing "pain as bad as you can imagine". Participant is asked to indicate rates of their pain on the day of presentation during resting, during function and physical examination as a baseline and, 30 minutes after PIN injection for each, 30 minutes after lateral apicondyle injection for each.

  Baseline, 30 minutes after PIN injection, 30 minutes after lateral epicondyle injection

Secondary Outcomes (4)

• Grip strength via dynamometer

  Baseline

• The Patient-Rated Tennis Elbow Evaluation (PRTEE)

  Baseline

• Disabilities of Arm, Shoulder, and Hand (DASH) Questionnaire

  Baseline

• The 36-Item Short Form Health Survey Questionnaire (SF-36)

  Baseline

Study Arms (1)

diagnostic single group

OTHER

Patients diagnosed with lateral epicondylitis with physical examinations will be evaluated with electrophysiology After electrophysiological evaluations, patients' effected extremity evaluated with ultrasonography for lateral epicondylitis and radial tunnel syndrome and compared with uneffected side 30 minutes after posterior interosseous nerve block with 1 cc 2% lidocaine with USG guide, full examination will be repeated for evaluation of NRS score changing to exact diagnose of radial tunnel syndrome 30 minutes after lateral epicondyle 1 cc 2% lidocaine injection with USG guide, full examination will be repeated for evaluation of NRS score changing to final diagnose of lateral epicondylitis

Diagnostic Test: diagnostic posterior interosseous nerve lidocaine injection

Interventions

diagnostic posterior interosseous nerve lidocaine injection DIAGNOSTIC_TEST

ultrasound guided posterior interosseous nerve and lateral epicondyle 1 ml 2% lidocaine injection

Also known as: diagnostic lateral epicondyle lidocaine injection

diagnostic single group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged 18-65 years
• Had persistent lateral elbow pain at least 6 months' duration with suspected lateral epicondylitis
• Be able to understand enough Turkish to complete the outcome questionnaire
• Patients whose informed consent was obtained for paticipation in the study

You may not qualify if:

• Fibromyalgia
• History of surgery in the elbow
• History of fracture that cause the deformity at radius/ulna
• Pregnancy or breastfeeding
• Inflammatuar arthropathy in upper extremities
• Osteoarthritis in the upper extremities
• Neurological disabilities that effect the upper extremity functions
• Cervical radiculopathy that effect the level of C6-C7

Sponsors & Collaborators

• Istanbul University - Cerrahpasa: lead

Study Sites (1)

Istanbul University-Cerrahpasa

Istanbul, 34098, Turkey (Türkiye)

Location

Related Publications (5)

• Ekstrom RA, Holden K. Examination of and intervention for a patient with chronic lateral elbow pain with signs of nerve entrapment. Phys Ther. 2002 Nov;82(11):1077-86.

  PMID: 12405872 BACKGROUND

• Ritts GD, Wood MB, Linscheid RL. Radial tunnel syndrome. A ten-year surgical experience. Clin Orthop Relat Res. 1987 Jun;(219):201-5.

  PMID: 3581572 BACKGROUND

• Newcomer KL, Martinez-Silvestrini JA, Schaefer MP, Gay RE, Arendt KW. Sensitivity of the Patient-rated Forearm Evaluation Questionnaire in lateral epicondylitis. J Hand Ther. 2005 Oct-Dec;18(4):400-6. doi: 10.1197/j.jht.2005.07.001.

  PMID: 16271686 BACKGROUND

• Tran N, Chow K. Ultrasonography of the elbow. Semin Musculoskelet Radiol. 2007 Jun;11(2):105-16. doi: 10.1055/s-2007-1001876.

  PMID: 18095243 BACKGROUND

• Gurcay E, Karaahmet OZ, Kara M, Onat SS, Ata AM, Unlu E, Ozcakar L. Ultrasonographic Evaluation of the Radial Nerves in Patients with Unilateral Refractory Lateral Epicondylitis. Pain Med. 2017 Mar 1;18(3):396-402. doi: 10.1093/pm/pnw181.

  PMID: 27477582 BACKGROUND

MeSH Terms

Conditions

Radial Neuropathy; Tennis Elbow

Condition Hierarchy (Ancestors)

Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Elbow Tendinopathy; Tendinopathy; Muscular Diseases; Musculoskeletal Diseases; Elbow Injuries; Arm Injuries; Wounds and Injuries; Tendon Injuries

Study Officials

• Zeynep Ulku Akarirmak

  Istanbul University - Cerrahpasa

  STUDY DIRECTOR

• Aslinur Keles Ercisli

  Istanbul University - Cerrahpasa

  PRINCIPAL INVESTIGATOR

• Deniz Palamar Kadioglu

  Istanbul University - Cerrahpasa

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: April 16, 2021
• First Posted: April 23, 2021
• Study Start: January 10, 2021
• Primary Completion: August 24, 2021
• Study Completion: December 16, 2021
• Last Updated: February 18, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)