Autologous Human Adipose-Derived Mesenchymal Stem Cells in Alzheimer's Disease

NCT04855955 | Unknown

• 1 other identifier: CTXSP0001
• Study Type: expanded_access
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

This is a single patient emergency expanded access clinical study to assess the safety of administering autologous AdMSCs to an incurable Alzheimer disease patient. The study subject will be evaluated for disease-associated severity according to symptoms, cognitive function, memory, and quality of life.

Conditions

Alzheimer Disease

Keywords

Autologous Adipose-derived Stem Cells (AdMSCs)

Interventions

Adipose-Derived Mesenchymal Stem Cells DRUG

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• The patient is diagnosed with later stage of Alzheimer Disease with sever cognitive disability.
• All current anti-Alzheimer medicines cannot prevent disease progression and the patient's mental and physical ability persistently declined
• Patient's legal guardian and caregiver must voluntarily sign an approved written consent form after ample explanation of the proposed therapy.

You may not qualify if:

• Current diagnosis of malignancy
• Renal/liver dysfunction: Exceed two times as normal subject
• Pregnant or nursing
• Received other trial drugs within 30 days after participation of this study
• Experienced major surgery or trauma in the last 14 days

Sponsors & Collaborators

• Celltex Therapeutics Corporation: lead

MeSH Terms

Conditions

Alzheimer Disease

Condition Hierarchy (Ancestors)

Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Mental Disorders

Study Officials

• Richard L Neel, M.D.

  Little Alsace Urgent Care Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: expanded access
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 30, 2021
• First Posted: April 22, 2021
• Last Updated: February 7, 2024

Record last verified: 2024-02