NCT04853784

Brief Summary

This is a comparison of totally laparoscopic and laparoscopic-assisted colon cancer resection, a prospective registration study comparing the safety and benefits of the two operations

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
650

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2021

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 6, 2021

Completed
15 days until next milestone

First Posted

Study publicly available on registry

April 21, 2021

Completed
10 days until next milestone

Study Start

First participant enrolled

May 1, 2021

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2023

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2023

Completed
Last Updated

April 21, 2021

Status Verified

April 1, 2021

Enrollment Period

2 years

First QC Date

April 6, 2021

Last Update Submit

April 18, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Incidence of postoperative complications

    Complication incidence 30 days after operation

    30 days after operation

Secondary Outcomes (9)

  • Operation time

    one hour after surgery

  • number of lymphnodes dissected

    During the operation

  • Length of surgical incision

    one week after surgery

  • Intraoperative blood loss

    one hour after surgery

  • Intraoperative conversion rate

    one hour after surgery

  • +4 more secondary outcomes

Study Arms (2)

Totally laparoscopic colon surgery

Totally laparoscopic colon surgery/intracorporeal anastomosis

Procedure: intracorporeal anastomosis

Laparoscopic-assited colon surgery

Laparoscopic-assited colon surgery/extracorporeal anastomosis

Procedure: intracorporeal anastomosis

Interventions

intracorporeal anastomosis

Also known as: extracorporeal anastomosis
Laparoscopic-assited colon surgeryTotally laparoscopic colon surgery

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with colon cancer

You may qualify if:

  • Age: 18-80 years old, male or female;
  • Colon cancer (ascending colon, transverse colon, descending colon, sigmoid colon) is diagnosed by histology or cytology;
  • The clinical stage is T1-4aN0-2M0; 4 No multiple distant metastases;
  • \. ECOG score 0-2; 6. Heart, lung, liver, and kidney functions can tolerate surgery; 7. Patients and their families can understand and are willing to participate in this clinical study, and sign an informed consent.

You may not qualify if:

  • Past history of malignant colorectal tumors or recent diagnosis combined with other malignant tumors;
  • Patients with intestinal obstruction, intestinal perforation, intestinal bleeding, etc. who need emergency surgery;
  • Neighboring organs need to be combined with organ resection;
  • New adjuvant therapy before surgery;
  • ASA grade ≥ grade IV and/or ECOG physical status score\> 2 points;
  • Those who have severe liver and kidney function, cardiopulmonary function, blood coagulation dysfunction, or combined with serious underlying diseases that cannot tolerate surgery;
  • History of severe mental illness;
  • Pregnant or lactating women;
  • Patients with other clinical and laboratory conditions considered by the investigator should not participate in the trial.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jilin University First Hospital

Changchun, Jilin, 130021, China

Location

MeSH Terms

Conditions

Colonic Neoplasms

Condition Hierarchy (Ancestors)

Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal Diseases

Central Study Contacts

Quan Wang, Prof.

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Month
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 6, 2021

First Posted

April 21, 2021

Study Start

May 1, 2021

Primary Completion

May 1, 2023

Study Completion

May 30, 2023

Last Updated

April 21, 2021

Record last verified: 2021-04

Data Sharing

IPD Sharing
Will not share

Locations