NCT05026268

Brief Summary

This is a randomized, controlled, "non-inferiority" trial to determine the non-difference in post-operative complications rate in laparoscopic right colectomy with intracorporeal or extracorporeal anastomosis formation.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
2

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2021

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 6, 2021

Completed
24 days until next milestone

First Posted

Study publicly available on registry

August 30, 2021

Completed
2 days until next milestone

Study Start

First participant enrolled

September 1, 2021

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2023

Completed
Last Updated

August 30, 2021

Status Verified

August 1, 2021

Enrollment Period

1.9 years

First QC Date

August 6, 2021

Last Update Submit

August 23, 2021

Conditions

Keywords

right colon cancerlaparoscopic right colectomyintracorporeal anastomosis

Outcome Measures

Primary Outcomes (1)

  • Post-operative complications rate

    The incidence and structure of postoperative complications according to the Clavien-Dindo scale (I-grade - any deviation from the normal course of the postoperative course without the need for pharmacological, surgical, endoscopic or interventional radiological interventions. drugs that are acceptable include antiemetics, antipyretics, analgesics, diuretics, and electrolytes. In addition, this grade includes a wound infection "stopped at the patient's bedside", V grades - Death of the patient).

    0 to 30 days

Secondary Outcomes (4)

  • The level of postoperative pain

    0 to 10 days

  • The time of activation of patients

    0 to 10 days

  • The amount of self-help of patients

    0 to 10 days

  • The time to discharge from hospital

    0 to 30 days

Study Arms (2)

Intracorporeal anastomosis

EXPERIMENTAL

A laparoscopic right colectomy will be performed according to the surgeons standard practice with the intracorporeal anastomosis performing.

Procedure: intracorporeal anastomosis

extracorporeal anastomosis

NO INTERVENTION

A laparoscopic right colectomy will be performed according to the surgeons standard practice.

Interventions

intracorporeal stapled "side-to-side" isoperistaltic anastomosis

Intracorporeal anastomosis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients age is 18 years and older
  • Patients with right colon cancer
  • Informed agreement

You may not qualify if:

  • Carcinomatosis
  • Primary tumor stage T4b
  • Refusal of anastomosis
  • Refusal of the patient to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

State Scientific Centre of Coloproctology, Russian Federation

Moscow, Russia

RECRUITING

MeSH Terms

Conditions

Colonic Neoplasms

Condition Hierarchy (Ancestors)

Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal Diseases

Central Study Contacts

Sergey Achkasov, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 6, 2021

First Posted

August 30, 2021

Study Start

September 1, 2021

Primary Completion

August 1, 2023

Study Completion

August 1, 2023

Last Updated

August 30, 2021

Record last verified: 2021-08

Locations