NCT04839796

Brief Summary

The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. The program aims to develop a comprehensive and integrated approach to disease prevention and community health. The researcher's cohort organizes healthcare outreaches for participants over the age of 20 residing in 64 administrative areas in Keelung city and new Taipei city. The researcher's sessions include a comprehensive health examination, health-related questionnaires, and disease awareness seminars. Biological samples, questionnaire information, and medical data obtained from researcher's participants are stored in researcher's core laboratory. Depersonalized data and samples are shared with partnering trials approved by the Chang Gung Memorial Hospital Institutional review board. The investigators are currently partnered with 18 clinical trials spanning across multiple disciplines such as urology, hepatology, metabolism, physical therapy, and psychology.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20,000

participants targeted

Target at P75+ for all trials

Timeline
210mo left

Started Aug 2013

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress43%
Aug 2013Aug 2043

Study Start

First participant enrolled

August 1, 2013

Completed
7.7 years until next milestone

First Submitted

Initial submission to the registry

March 28, 2021

Completed
12 days until next milestone

First Posted

Study publicly available on registry

April 9, 2021

Completed
22.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2043

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2043

Last Updated

April 9, 2021

Status Verified

January 1, 2021

Enrollment Period

30 years

First QC Date

March 28, 2021

Last Update Submit

April 7, 2021

Conditions

Keywords

NTCMRCMaintenance ProjectHealth Care Activities

Outcome Measures

Primary Outcomes (4)

  • Participant died during the observation period.

    Investigators keep in touch with participants and invite them to participate in healthcare outreaches every year.

    From 2013 Augus to Feb 2021

  • Dementia

    The AD8 dementia screening interview is used to detect the early signs of dementia. Using the items in the form to check whether participants have similar symptoms, so as to detect and treat them as soon as possible.

    From 2013 Augus to Feb 2021

  • Chronic Kidney Disease

    Chronic kidney disease is a type of kidney disease in which there is gradual loss of kidney function over a period of months to years.

    From 2013 Augus to Feb 2021

  • Liver cancer

    Participant suffers from liver cancer

    From 2013 Augus to Feb 2021

Study Arms (2)

Participants residing in urban areas

Urban residents enjoy convenient transportation, have access to abundant medical resources, have more job opportunities, and are on average younger but are also exposed to more air pollution.

Participants residing in rural areas

Rural residents have less access to transportation, medical resources, and job prospects comparatively and are comparatively older. However, Rural residents are exposed to less pollution in general.

Eligibility Criteria

Age20 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Participants who enroll in these community health activities and meet the following conditions: 1. Over the age of 20. 2. Residing in 64 administrative areas in Keelung city and new Taipei city.

You may qualify if:

  • Residing in Keelung city and new Taipei city.
  • Mobile health and mental health
  • Participating in healthcare outreaches

You may not qualify if:

  • Under 20 years old
  • Participant without judgment
  • Participant has HIV

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Community Medicine Research Center Chang Gung Memorial Hospital Keelung,Taiwan,204

Keelung, Taiwan

RECRUITING

Related Publications (3)

  • Hsu PW, Yeh CH, Lo CJ, Tsai TH, Chan YH, Chou YJ, Yang NI, Cheng ML, Sheu WH, Lai CC, Sytwu HK, Tsai TF. Trans-omics analyses identify the biochemical network of LPCAT1 associated with coronary artery disease. Biomark Res. 2025 Aug 20;13(1):107. doi: 10.1186/s40364-025-00821-y.

  • Wei YC, Chen CK, Lin C, Shyu YC, Chen PY. Life After Traumatic Brain Injury: Effects on the Lifestyle and Quality of Life of Community-Dwelling Patients. Neurotrauma Rep. 2024 Mar 1;5(1):159-171. doi: 10.1089/neur.2023.0113. eCollection 2024.

  • Wu IW, Tsai TH, Lo CJ, Chou YJ, Yeh CH, Cheng ML, Lai CC, Sytwu HK, Tsai TF. Discovery of a Biomarker Signature That Reveals a Molecular Mechanism Underlying Diabetic Kidney Disease via Organ Cross Talk. Diabetes Care. 2022 Jun 2;45(6):e102-e104. doi: 10.2337/dc22-0145. No abstract available.

Study Officials

  • Yu Chiau Shyu, PHD

    Community Medicine Research Center,Chang Gung Memorial Hospital,Keelung branch

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Yu Chiau Shyu, PHD

CONTACT

Rou Ling Cho, PHD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 28, 2021

First Posted

April 9, 2021

Study Start

August 1, 2013

Primary Completion (Estimated)

August 1, 2043

Study Completion (Estimated)

August 1, 2043

Last Updated

April 9, 2021

Record last verified: 2021-01

Data Sharing

IPD Sharing
Will not share

Locations