Effects of High-intensity Interval Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke

NCT04835740 | Completed DMC

• 1 other identifier: IRB/ASCRH/0006/2020
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Hemiplegia is one of the most common sequelae of stroke. Stroke is the leading cause of disability in adults all around the world. Stroke survivors can suffer several neurological impairments and deficits which have an important impact on patient's quality of life and which increase the costs for health and social services. After stroke, impairments in ADLs and functional status, deterioration in health related quality of life can be seen. The purpose of this study is to Determine the effect of Aerobic exercise training on Balance, Walking capacity and quality of life in sub-acute stroke.

Conditions

Stroke, Ischemic; Cerebrovascular Accident

Keywords

Cerebrovascular accident; Treadmill Training; High-intensity interval training; Walking capacity.

Outcome Measures

Primary Outcomes (1)

• 6 Minute walk Test

  To determine the cardiorespiratory fitness of individual after sub-acute stroke.

  5 weeks

Secondary Outcomes (2)

• Berg Balance test and rating scale

  5 weeks

• Stroke Impact scale

  5 weeks

Study Arms (2)

Conventional Rehabilitation

ACTIVE COMPARATOR

Based on the functional capacity of each participant, customized Aerobic exercise plan was designed by the on-site physiotherapist.

Other: High intensity Interval Training

Combined Training (conventional rehabilitation plus high-intensity interval training):

EXPERIMENTAL

The patients received 40 minutes of High intensity interval treadmill training in addition to their normal conventional rehabilitation.

Other: High intensity Interval Training

Interventions

High intensity Interval Training OTHER

All the participants underwent 5 weeks of High intensity interval training.

Combined Training (conventional rehabilitation plus high-intensity interval training):; Conventional Rehabilitation

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• to 75 years of age.
• Ischemic Stroke that occurred in the recent 3 months.
• Who can walk independently or by using assistive device.
• Have a minimum Chedoke McMaster Stroke Assessment (CMSA) leg impairment score of 3 but less than 7.

You may not qualify if:

• Patients were excluded from the study if they have a stroke that occurs more than 3 months.
• Hemorrhagic Stroke.
• If resting blood pressure more than 160/100 even after taking medications
• Have by-pass surgery in recent 3 months.
• Other musculoskeletal problems which restrict the patient's ability to do aerobic activity.

Sponsors & Collaborators

• Akhtar Saeed Medical and Dental College: lead

Study Sites (1)

Akhtar Saeed Hospital

Lahore, Pakistan

Location

MeSH Terms

Conditions

Ischemic Stroke; Stroke

Interventions

High-Intensity Interval Training

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist

Study Record Dates

• First Submitted: April 6, 2021
• First Posted: April 8, 2021
• Study Start: October 5, 2020
• Primary Completion: November 15, 2020
• Study Completion: March 16, 2021
• Last Updated: April 8, 2021

Record last verified: 2021-04

Locations

PA (1)