Temporal Trends of COronary Artery Disease and PEripheral Artery Disease (COPE) in Korea

NCT04834843 | Completed

• 1 other identifier: 2020AN0279
• Study Type: observational
• Target: 700,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

Cardiovascular disease (CVD) is caused by atherosclerosis of the artery and is classified into coronary artery disease, cerebrovascular disease, and peripheral arterial disease, depending on the location of the artery and the target organs. However, since CVD share a similar pathophysiology and the probability of incidence of other CVD in CVD patients is very high. It is thought that CVD incidence and mortality can be reduced by predicting the degree of incidence of other CVD in CVD patients. The aim of this study is to investigate the incidence and mortality of other CVD diseases in CVD patients.

Conditions

Coronary Artery Disease; Peripheral Artery Disease; Cardiovascular Diseases

Outcome Measures

Primary Outcomes (1)

• Incidence of coronary artery disease, cerebrovascular disease, peripheral arterial disease

  Among all Koreans, percentage (%) of patients with a history of being diagnosed with CVD and underwent in-hospital treatment

  Up to 10 years

Secondary Outcomes (1)

• 1-year mortality

  Up to 1 year

Interventions

Observational study, no intervention OTHER

Observational study, no intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

People aged at least 18 years old with CAD, PAD, or cerebrovascular disease were identified from Korean national health insurance using International Classification of Diseases, tenth revision (ICD-10) codes.

You may qualify if:

• Koreans who diagnosed with coronary artery disease between 2009 and 2018
• Koreans who diagnosed with peripheral artery disease between 2009 and 2018
• Koreans who diagnosed with cerebrovascular disease between 2009 and 2018
• more than 18 years old

You may not qualify if:

• less than 18 years old

Sponsors & Collaborators

• Wonju Severance Christian Hospital: lead

Related Publications (4)

• Sundaram V, Bloom C, Zakeri R, Halcox J, Cohen A, Bowrin K, Briere JB, Banerjee A, Simon DI, Cleland JGF, Rajagopalan S, Quint JK. Temporal trends in the incidence, treatment patterns, and outcomes of coronary artery disease and peripheral artery disease in the UK, 2006-2015. Eur Heart J. 2020 May 1;41(17):1636-1649. doi: 10.1093/eurheartj/ehz880.

  PMID: 31883328 RESULT

• Bhatt DL, Steg PG, Ohman EM, Hirsch AT, Ikeda Y, Mas JL, Goto S, Liau CS, Richard AJ, Rother J, Wilson PW; REACH Registry Investigators. International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA. 2006 Jan 11;295(2):180-9. doi: 10.1001/jama.295.2.180.

  PMID: 16403930 RESULT

• Ahn S, Park YJ, Min SI, Kim SY, Ha J, Kim SJ, Kim HS, Yoon BW, Min SK. High prevalence of peripheral arterial disease in Korean patients with coronary or cerebrovascular disease. J Korean Med Sci. 2012 Jun;27(6):625-9. doi: 10.3346/jkms.2012.27.6.625. Epub 2012 May 26.

  PMID: 22690093 RESULT

• Sogaard M, Nielsen PB, Skjoth F, Eldrup N, Larsen TB. Temporal Changes in Secondary Prevention and Cardiovascular Outcomes After Revascularization for Peripheral Arterial Disease in Denmark: A Nationwide Cohort Study. Circulation. 2021 Mar 2;143(9):907-920. doi: 10.1161/CIRCULATIONAHA.120.047994. Epub 2020 Dec 10.

  PMID: 33300375 RESULT

MeSH Terms

Conditions

Coronary Artery Disease; Peripheral Arterial Disease; Cardiovascular Diseases

Interventions

Observation

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Atherosclerosis; Peripheral Vascular Diseases

Intervention Hierarchy (Ancestors)

Methods; Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: April 5, 2021
• First Posted: April 8, 2021
• Study Start: January 1, 2009
• Primary Completion: December 31, 2018
• Study Completion: December 31, 2020
• Last Updated: April 8, 2021

Record last verified: 2021-04

Data Sharing

• IPD Sharing: Will not share