NCT04829578

Brief Summary

Chronic idiopathic pruritus (CIP) is a frequent and disabling condition, for which there is no specific treatment. It was shown previously that hypnosis can relieve painful sensations. Pain and pruritus share many similarities regarding sensory receptors and pathways, suggesting that hypnosis might help relief CIP.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 26, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 2, 2021

Completed
11 days until next milestone

Study Start

First participant enrolled

April 13, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 13, 2021

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2022

Completed
Last Updated

March 24, 2026

Status Verified

March 1, 2026

Enrollment Period

5 months

First QC Date

March 26, 2021

Last Update Submit

March 20, 2026

Conditions

Chronic Idiopathic Pruritus

Outcome Measures

Primary Outcomes (1)

  • Change From Baseline in Pruritus Numeric Rating Scale

    Assessment of the intensity of pruritis in Pruritus Numeric Rating Scal; the minimum and maximum values 0 to 10

    Day 84

Secondary Outcomes (6)

  • Change From Baseline in Pruritus Verbal Rating Scale

    Day 84

  • Change From Baseline in Sleeping Scale

    Day 84

  • Change From Baseline in DLQI scale

    Day 84

  • Change From Baseline in HAD scale

    Day 84

  • Change From Baseline in usage of topical steroids

    Day 84

  • +1 more secondary outcomes

Study Arms (1)

Hypnosis

OTHER

hyspnosis treatment

Other: Hypnosis

Interventions

HypnosisOTHER

Chronic idiopathic pruritus is treated by hypnosis

Hypnosis

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male or female of at least 18 years at screening
  • Diagnosis of chronic (at least 6 wks.) idiopathic pruritus
  • Pruritus Numeric Rating Scale \> = 4

You may not qualify if:

  • Pruritus caused by a dermatological or a systemic conditions
  • Suicidal crisis, moderate, or severe
  • Psychosis (schizophrenia, persistent delusional disorder)
  • Bipolar disorder, not stabilized or decompensating
  • Personality disorder, decompensated

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chu de Nice

Nice, France, 06000, France

Location

Related Publications (1)

  • Bertold C, Delaunay P, Cathelineau AC, Chassang M, Passeron T, Bahadoran P. Efficacy of hypnotherapy in chronic idiopathic pruritus: a single-arm prospective pilot study. Br J Dermatol. 2024 Sep 18;191(4):644-645. doi: 10.1093/bjd/ljae244. No abstract available.

    PMID: 38913389RESULT

MeSH Terms

Interventions

Hypnosis

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • BAHADORAN PHILIPPE

    Centre Hospitalier Universitaire de Nice

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 26, 2021

First Posted

April 2, 2021

Study Start

April 13, 2021

Primary Completion

September 13, 2021

Study Completion

October 31, 2022

Last Updated

March 24, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)