Effect of BMI on Postoperative Morbidities of Orthopaedic Procedures

NCT04827888 | Completed

• 1 other identifier: 20210330BMI
• Study Type: observational
• Target: 76,189
• Locations: 1 country
• Sites: 1

Brief Summary

Obesity is associated with poor surgical outcome and complications. The literature does not provide a comprehensive view on the effect of body mass index (BMI) on perioperative outcomes in orthopedic surgeries. Therefore, we aim to determine the effect of BMI on 30-day perioperative outcomes in patients undergoing the first 25 most commonly performed orthopedic surgeries using a retrospective cohort study design. The knowledge of the effect of BMI on orthopedic surgeries will improve the knowledge of surgeons about the expected morbidities.

Conditions

Orthopedic Procedures; Obesity

Keywords

weight; orthopedic surgery; BMI; Post-Op Complication

Outcome Measures

Primary Outcomes (1)

• Composite morbidity

  Composite morbidity is defined as the presence of any of the specific morbidities during the 30-days following surgery as recorded in the ACS-NSQIP database. The odds ratio of composite morbidity for each BMI group will be calculated as compared to normal-weight group.

  within the 30 days following the surgery

Secondary Outcomes (10)

• mortality

  within the 30 days following the surgery

• wound

  within the 30 days following the surgery

• cardiac

  within the 30 days following the surgery

• respiratory

  within the 30 days following the surgery

• urinary

  within the 30 days following the surgery

Study Arms (5)

underweight

patients who underwent one of the 25 common orthopaedic surgeries and have a body mass index (BMI) of \<18.5kg/m2

Procedure: Orthopaedic surgery

normal-weight

patients who underwent one of the 25 common orthopaedic surgeries and have a BMI between 18.5kg/m2 and 24.9kg/m2

Procedure: Orthopaedic surgery

overweight

patients who underwent one of the 25 common orthopaedic surgeries and have a BMI between 25kg/m2 and 29.9kg/m2

Procedure: Orthopaedic surgery

mildly obese

patients who underwent one of the 25 common orthopaedic surgeries and have a BMI between 30kg/m2 and 34.9kg/m2

Procedure: Orthopaedic surgery

moderately-to-severely obese

patients who underwent one of the 25 common orthopaedic surgeries and have a BMI ≥35kg/m2

Procedure: Orthopaedic surgery

Interventions

Orthopaedic surgery PROCEDURE

One of the 25 most common orthopedic surgeries reported in the database which are the following as per surgical types: spine surgery (CPT codes 63030, 63047, 22612, 22551 or 22558), trauma (CPT codes 27236, 27125, 27244, 27814, or 27792), sports medicine injuries (CPT codes 29881, 29827, 29880, 29888, 29826, 29877, 29807, or 23412), or joint arthroplasty (CPT codes 27447, 27130, 23472, 27487, 27134, 27446, or 27486).

mildly obese; moderately-to-severely obese; normal-weight; overweight; underweight

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Representative of the population from ACS-NSQIP

You may not qualify if:

• All patients who have undergone any of the 25 most common orthopedic procedures as primary procedure as identified through the CPT codes
• All patients whose BMI was not reported

Sponsors & Collaborators

• American University of Beirut Medical Center: lead

Study Sites (1)

American University of Beirut Medical Center

Beirut, 11-236, Lebanon

Location

MeSH Terms

Conditions

Obesity; Body Weight; Postoperative Complications

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Pathologic Processes

Study Officials

• Muhyeddine Al-Taki

  American University of Beirut Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Target Duration: 30 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Clinical Surgery

Study Record Dates

• First Submitted: March 30, 2021
• First Posted: April 1, 2021
• Study Start: January 1, 2012
• Primary Completion: December 31, 2015
• Study Completion: December 31, 2020
• Last Updated: April 5, 2021

Record last verified: 2021-04

Data Sharing

• IPD Sharing: Will not share

Locations

LE (1)