Occurrence, Trends, Management and Outcomes of Patients Hospitalized With Myocarditis

NCT04827706 | Unknown DMC

• 1 other identifier: MYO-PL
• Study Type: observational
• Target: 19,978
• Locations: 1 country
• Sites: 1

Brief Summary

The epidemiology of myocarditis is largely unknown and based mainly on small single-center studies. The study aim to evaluate the current incidence, clinical characteristics and outcomes of patients hospitalized due to myocarditis in a general population.

Conditions

Myocarditis; Sudden Cardiac Death; Cardiomyopathies; Arrythmia; Heart Failure

Keywords

cardiomyopathy; children; endomyocardial biopsy; epidemiology; heart failure; cardiac magnetic resonance

Outcome Measures

Primary Outcomes (8)

• Characteristics of myocarditis in Poland

  Distribution of myocarditis incidence regarding to voivodeship/ district, city size (number of residents), hospital and ward type of admission

  10 years

• Seasonal occurrence

  Seasonal occurrence rate of myocarditis regarding to gender and age

  10 years

• In-hospital mortality

  Occurrence of all-cause death during initial hospitalization for myocarditis

  10 years

• Long-term mortality

  Occurrence of all-cause death at 10-year observation.

  10 years

• Analysis of in-hospital course of patients with myocarditis.

  Hospitalization length

  10 years

• Trends in the utilisation rate of diagnostic procedures.

  Trends in the application rate of diagnostic procedures aimed at diagnosing myocarditis (i.e. cardiac magnetic resonance, endomyocardial biopsy, troponin, echocardiography, coronary angiography)

  10 years

• Occurrence of recurrent myocarditis

  Occurrence of recurrent hospitalization for myocarditis

  10 years

• Occurrence of heart failure

  Occurrence of heart failure hospitalization after diagnosis of myocarditis

  10 years

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients with first myocarditis hospitalization in Poland in observed time period.

You may qualify if:

• first myocarditis hospitalization

Sponsors & Collaborators

• Medical University of Warsaw: lead

Study Sites (1)

First Department of Cardiology, Medical University of Warsaw

Warsaw, 02-097, Poland

Location

Related Publications (2)

• Ozieranski K, Tyminska A, Chabior A, Kruk M, Kon B, Maciejewski C, Opolski G, Grabowski M. Sex differences in incidence, management, and outcomes in adult patients aged over 20 years with clinically diagnosed myocarditis in the last 10 years: data from the MYO-PL nationwide database. Pol Arch Intern Med. 2022 Apr 28;132(4):16199. doi: 10.20452/pamw.16199. Epub 2022 Jan 27.

  PMID: 35084153 DERIVED

• Ozieranski K, Tyminska A, Kruk M, Kon B, Skwarek A, Opolski G, Grabowski M. Occurrence, Trends, Management and Outcomes of Patients Hospitalized with Clinically Suspected Myocarditis-Ten-Year Perspectives from the MYO-PL Nationwide Database. J Clin Med. 2021 Oct 12;10(20):4672. doi: 10.3390/jcm10204672.

  PMID: 34682794 DERIVED

MeSH Terms

Conditions

Myocarditis; Death, Sudden, Cardiac; Cardiomyopathies; Arrhythmias, Cardiac; Heart Failure

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Heart Arrest; Death, Sudden; Death; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Marcin Grabowski, Professor

  Medical University of Warsaw

  STUDY CHAIR

• Grzegorz Opolski, Professor

  Medical University of Warsaw

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 8, 2021
• First Posted: April 1, 2021
• Study Start: January 1, 2009
• Primary Completion: December 31, 2021
• Study Completion: December 31, 2021
• Last Updated: April 1, 2021

Record last verified: 2021-03

Locations

PL (1)