Evaluating the Impact of Focused Muscle Contraction Therapy in Retire APF Players

NCT04822311 | Completed

• 1 other identifier: 2019-0905
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

This study will investigate the effects of an exercise intervention on retired American professional football (APF) players. A total of 20 retired APF players (≥ 18 years of age), who suffer from chronic pain, will be enrolled. The study duration for each participants will be 18 months. Enrolled participants will perform a 18 months exercise intervention which involves 90 exercise rehabilitation training visits. In addition, participants will also be tested on various measures of health and function both at baseline (prior to intervention), at 6 months, 12 months, and 18 months (post intervention). All testing and result interpretation will be performed by trained research personnel. Participants are not University of Illinois at Chicago (UIC) participants; however, study testing visits will occur at UIC. All exercise intervention training visits will occur at Gh Fitlab.

Conditions

Chronic Pain Due to Injury; Acute Pain; Depression; Brain Injuries

Outcome Measures

Primary Outcomes (1)

• Rate at which exercise will positively affect body composition

  1\. Exercise will positively affect body composition. With this hypothesis we will test whether muscle strength (dynamometer) and muscle mass (DEXA scan) changes after 6 months, 12 months, 18 months of an exercise intervention. Baseline measurement will be performed before the intervention, at 6 months, 12 months, and at the end of the study (18 months) with muscle mass measured by DEXA and strength measured again by dynamometer.

  18 months

Secondary Outcomes (3)

• Rate at which participants will see improvements in their physical abilities

  18 months

• Rate at which participants will have overall improved sense of well-being, increased independence, quality of life, and decreased depression

  18 months

• Rate at which participants will display alterations in brain wave function

  18 Months

Study Arms (1)

Investigate the effects of an exercise intervention on retired APF players

EXPERIMENTAL

20 retired APF players (≥ 18 years of age), who suffer from chronic pain, will be enrolled.

Behavioral: Experimental: Investigate the effects of an exercise intervention on retired APF players

Interventions

Experimental: Investigate the effects of an exercise intervention on retired APF players BEHAVIORAL

Enrolled participants will perform a 18 months exercise intervention which involves 90 exercise rehabilitation training visits. In addition, participants will also be tested on various measures of health and function both at baseline (prior to intervention), at 6 months, 12 months, and 18 months (post intervention).

Investigate the effects of an exercise intervention on retired APF players

Eligibility Criteria

• Age: 18 Years+
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Retired APF player (there is no minimum duration or career length required no minimum duration or career length required)
• years of age and older

You may not qualify if:

• This study will exclude non-English speaking participants as they would not be able to complete intensive survey requirement of the study as all surveys will be administered in the English language.

Sponsors & Collaborators

• University of Illinois at Chicago: lead

Study Sites (1)

University of Illinois at Chicago

Chicago, Illinois, 60612, United States

Location

MeSH Terms

Conditions

Acute Pain; Depression; Brain Injuries

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavioral Symptoms; Behavior; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Craniocerebral Trauma; Trauma, Nervous System; Wounds and Injuries

Study Officials

• Enrico Benedetti, MD

  University of Illinois at Chicago

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Warren H. Cole Chair in Surgery, Professor and Head of Surgery, Medical Director, Abdominal Organ Transplant Program

Study Record Dates

• First Submitted: March 25, 2021
• First Posted: March 30, 2021
• Study Start: October 24, 2019
• Primary Completion: April 18, 2021
• Study Completion: May 15, 2023
• Last Updated: June 9, 2023

Record last verified: 2023-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)