Differences in Nutrient Use During Exercise Between Children of Varying Body Mass Indices and Fitness Levels

NCT04819308 | Active Not Recruiting

• 1 other identifier: 261146
• Study Type: observational
• Target: 95
• Locations: 1 country
• Sites: 1

Brief Summary

Children who have previously participated in the study "MI Energy" will be invited to participate in "SUPER kids". Investigators want to better understand differences in nutrient use (e.g., fatty acid and carbohydrate) during rest and exercise in children of varying body types and activity levels.

Conditions

Obesity

Keywords

Children; Kids; Physical Activity; Exercise; Substrate Oxidation; Fat Oxidation; Carbohydrate Oxidation; Fitness; Nutrient; Obesity

Outcome Measures

Primary Outcomes (1)

• Substrate Oxidation

  Carbohydrate oxidation and fatty acid oxidation quantified using breath samples measured by indirect calorimetry

  24 months

Eligibility Criteria

• Age: 8 Years - 11 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Healthy children ages 8-11, who have previously participated in the study "MI Energy".

You may qualify if:

• Boys or girls
• Ages 8-11 years
• All races
• All ethnicities
• All BMIs
• Children who completed a dual-energy x-ray absorptiometry (DXA) scan during "MI Energy" (IRB Protocol: 260376)
• Children who completed a fitness test during "MI Energy" (IRB Protocol: 260376) and achieved peak oxygen uptake (VO2 peak)
• All fitness levels \[VO2 peak already determined under "MI Energy" (IRB Protocol: 260376)\]
• Children whose parents consented to the following in the "MI Energy" (IRB Protocol: 260376) study:
• A) be contacted about future follow-up studies to "MI Energy", and having the data that is collected about their child in "MI Energy" being used also in these follow-up studies; and B) information collected in the "MI Energy" study may be used in future research related to bioenergetics (for example, blood cell mitochondria function), nutrition, obesity, cardiovascular health, or development; and C) any biological samples collected in the "MI Energy" study may be used in future research related to bioenergetics (for example, blood cell mitochondria function), nutrition, obesity, cardiovascular health, or development.

You may not qualify if:

• Participants who have been excluded from participation in the study "MI Energy" (IRB Protocol: 260376).
• Participants whose parents report any change in medical history that may potentially affect participation and/or study outcomes as determined by PI.
• Participants whose parents report food allergies or intolerances to nuts, wheat, dairy, or eggs.
• Participants whose parents report unwillingness to follow dietary standardization.

Sponsors & Collaborators

• Arkansas Children's Hospital Research Institute: lead

Study Sites (1)

Arkansas Children's Nutrition Center

Little Rock, Arkansas, 72202, United States

Location

Related Links

• Arkansas Children's Nutrition Center webpage

MeSH Terms

Conditions

Obesity; Motor Activity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Study Officials

• Elisabet Borsheim, PhD

  Arkansas Children's Hospital Research Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 25, 2021
• First Posted: March 26, 2021
• Study Start: March 18, 2021
• Primary Completion: July 1, 2024
• Study Completion: December 1, 2025
• Last Updated: February 25, 2025

Record last verified: 2024-09

Locations

US (1)