Mulligan Mobilization With Movement Versus Macquarie Injury Management Group in Function and Pain of Knee Osteoarthritis

NCT04818307 | Completed DMC

• 1 other identifier: REC/Lhr/1064
• Study Type: interventional
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

Knee pain is one of the most usual pain that commonly affects people especially in the late age. It can be caused by osteoarthritis, poor posture or sitting position, bad bending or improper lifting. It is usually not caused by a serious illness. It is the most common cause of disability. To compare the long term effects of Mulligan Mobilization with Movement versus Macquarie Injury Management Group on pain and function of knee osteoarthritis.

Conditions

Knee Osteoarthritis

Keywords

Knee Pain; Movement with Mobilization

Outcome Measures

Primary Outcomes (2)

• Visual Analogue scale

  The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."

  6 months

• WOMAC

  The scores for each subscale are summed up, with a possible score range of 0-20 for Pain, 0-8 for Stiffness, and 0-68 for Physical Function. Usually a sum of the scores for all three subscales gives a total WOMAC score, however there are other methods that have been used to combine scores.

  6 months

Study Arms (2)

Macquarie Injury Management group

EXPERIMENTAL

Other: Macquarie Injury Management group

Mulligan Mobilization with Movement

ACTIVE COMPARATOR

Other: Mulligan Mobilization with Movement

Interventions

Macquarie Injury Management group OTHER

Group A was treated by MIMG (soft tissue mobilization) with base line treatment (Hot pack for 10 mint, Quadriceps Isometrics, Stretching). For the application of technique subject lies supine with extended knee, therapist places both hands on the knee and gently apply soft tissue release. This procedure was applied for 2 to 3 minutes.

Macquarie Injury Management group

Mulligan Mobilization with Movement OTHER

Group B was treated by Mulligan Mobilization with movement with base line treatment (Hot Pack for 10 mints, Quadriceps Isometrics, Stretching). For the application of technique subject lies supine with 30 degree knee flexion, therapist places right hand below the knee and left hand above the knee. Apply the lateral glide on the joint. This procedure was applied for 3 times.

Mulligan Mobilization with Movement

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ACR criteria for knee will be over age 50
• less than 30 minutes of morning stiffness,
• Crepitus on active motion,
• Tenderness
• Enlargement
• No palpable warmth of synovium.
• Osteoarthritis grade 1 and 2 by Kelly-green and Lawrence method.

You may not qualify if:

• Any surgical procedure done in past 6 months and metal implants in lower extremity.
• Any infection and neoplastic disorder.
• Post traumatic knee stiffness.
• Secondary knee O A peripheral vascular disease

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Riphah Rehabilitation Center

Lahore, Punjab Province, 54000, Pakistan

Location

Related Publications (6)

• Kandada S, Heggannavar A. Effect of Mulligan's MWM versus Macquarie Injury Management Group (MIMG) protocol on pain and function in osteoarthritis of knee: a randomised clinical trial. IJTRR. 2015;4(4):125-31.

  BACKGROUND

• Bhatia D, Bejarano T, Novo M. Current interventions in the management of knee osteoarthritis. J Pharm Bioallied Sci. 2013 Jan;5(1):30-8. doi: 10.4103/0975-7406.106561.

  PMID: 23559821 BACKGROUND

• Felson DT. The epidemiology of knee osteoarthritis: results from the Framingham Osteoarthritis Study. Semin Arthritis Rheum. 1990 Dec;20(3 Suppl 1):42-50. doi: 10.1016/0049-0172(90)90046-i.

  PMID: 2287948 BACKGROUND

• Felson DT, Gale DR, Elon Gale M, Niu J, Hunter DJ, Goggins J, Lavalley MP. Osteophytes and progression of knee osteoarthritis. Rheumatology (Oxford). 2005 Jan;44(1):100-4. doi: 10.1093/rheumatology/keh411. Epub 2004 Sep 20.

  PMID: 15381791 BACKGROUND

• Cooper C, McAlindon T, Coggon D, Egger P, Dieppe P. Occupational activity and osteoarthritis of the knee. Ann Rheum Dis. 1994 Feb;53(2):90-3. doi: 10.1136/ard.53.2.90.

  PMID: 8129467 BACKGROUND

• Alshami AM. Knee osteoarthritis related pain: a narrative review of diagnosis and treatment. Int J Health Sci (Qassim). 2014 Jan;8(1):85-104. doi: 10.12816/0006075.

  PMID: 24899883 BACKGROUND

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

Movement

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Physiological Phenomena; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Maryam Shabbir

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 25, 2021
• First Posted: March 26, 2021
• Study Start: April 1, 2020
• Primary Completion: November 30, 2020
• Study Completion: December 30, 2020
• Last Updated: September 2, 2021

Record last verified: 2021-08

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)