NCT04817397

Brief Summary

  1. 1.ry outcome includes the correlation between lymphocyre /neurtophll ratio (LNR) and mortality rate during hospital stay in the ICU admitted COVID 19 patients.
  2. 2.ry outcome(s) include the LNR and its correlation with ICU stay, the need for mechanical ventilation, renal impairment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 20, 2021

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

March 23, 2021

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 26, 2021

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2021

Completed
Last Updated

October 12, 2021

Status Verified

October 1, 2021

Enrollment Period

4 months

First QC Date

March 23, 2021

Last Update Submit

October 9, 2021

Conditions

Covid19

Outcome Measures

Primary Outcomes (1)

  • The Lymphocyte/neutrophil ratio

    The Lymphocyte/neutrophil ratio as a prognostic index for short term outcome in the ICU admitted COVID-19 adult patients

    up to 30 days

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study will conducted on admitted patients that diagnosed as COVID at Assiut university hospitals

You may qualify if:

  • Adult patients (aged ≥18 years)
  • Patients who need non-invasive ventilation (NIV or CPAP) or invasive ventilation (intubation)

You may not qualify if:

  • Previous diagnosis of severe liver or kidney failure.
  • Patients with Human Immunodeficiency Virus (HIV) infection.
  • Patients with previous hematological diseases (Leukemia) that condition alterations in blood counts.
  • Consumption of treatments with any type of immunosuppressants prior to admission that conditions low lymphocytes.
  • Patients with bone marrow depression.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Assuit University

Asyut, Egypt

Location

Related Links

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor Emad Zarief kamel

Study Record Dates

First Submitted

March 23, 2021

First Posted

March 26, 2021

Study Start

March 20, 2021

Primary Completion

July 30, 2021

Study Completion

August 30, 2021

Last Updated

October 12, 2021

Record last verified: 2021-10

Locations

EG(1)