NCT04806009

Brief Summary

Insomnia has significantly negative impact on work, quality of life, psycho-somatic health on individuals and imposes substantial economic burdens on society. Mindfulness-based interventions (MBIs) have shown its efficacy in the treatment of insomnia, however the effect of online MBIs need more studies to verify. This study aims to compare the effectiveness of an online MBI named 'Mindful Living With Insomnia (MLWI)' to online CBI-I for insomnia.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2022

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 7, 2021

Completed
12 days until next milestone

First Posted

Study publicly available on registry

March 19, 2021

Completed
10 months until next milestone

Study Start

First participant enrolled

January 1, 2022

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2023

Completed
Last Updated

March 19, 2021

Status Verified

March 1, 2021

Enrollment Period

12 months

First QC Date

March 7, 2021

Last Update Submit

March 17, 2021

Conditions

Keywords

insomniamindfulness-based interventionCognitive Behavioral Therapy for insomniaonline

Outcome Measures

Primary Outcomes (1)

  • change of sleep quality

    The 19-item Pittsburgh Sleep Quality Index (PSQI) measured sleep quality subjectively and assesses sleep disturbances during the past month on a 4-point Likert scale of 0 -3.A lower global PSQI score indicates better sleep quality.

    Outcomes will be evaluated at baseline, the end of the 6-week Intervention Period, and at a 3-month follow-up

Secondary Outcomes (6)

  • change of perceived stress

    Outcomes will be evaluated at baseline, the end of the 6-week Intervention Period, and at a 3-month follow-up

  • change of depression

    Outcomes will be evaluated at baseline, the end of the 6-week Intervention Period, and at a 3-month follow-up

  • change of mindfulness

    Outcomes will be evaluated at baseline, the end of the 6-week Intervention Period, and at a 3-month follow-up

  • change of anxiety

    Outcomes will be evaluated at baseline, the end of the 6-week Intervention Period, and at a 3-month follow-up

  • change of severity of insomnia symptoms

    Outcomes will be evaluated at baseline, the end of the 6-week Intervention Period, and at a 3-month follow-up

  • +1 more secondary outcomes

Study Arms (2)

'Mindful Living With Insomnia (MLWI)' Intervention via WeChat mini-program

EXPERIMENTAL

Participants in the Intervention Group will receive the MLWI Intervention after follow the WeChat mini-program. The MLWI Intervention was developed and presented by the Principle Investigator (PI) who is a psychiatrist and have completed the Training of Mindfulness Facilitation (TMF) program at the Mindful Awareness Research Center of University of California, Los Angeles.

Behavioral: 'Mindful Living With Insomnia (MLWI)' Intervention via WeChat mini-program

'Cognitive Behavioral Therapy for insomnia (CBT-I)'via WeChat mini-program

ACTIVE COMPARATOR

Participants in the Control Group will receive CBT-I after follow the WeChat mini-program. The CBT-I was developed and presented by a researcher who is a psychiatrist/psychologist and have many years' experiences in CBT.

Behavioral: 'Cognitive Behavioral Therapy for insomnia (CBT-I)'via WeChat mini-program

Interventions

The MLWI Intervention involves 12 sessions over 6 weeks course, 2 sessions a week and 0.5 hours per session. Two new sessions of online lessons will be updated weekly in the 6 weeks. Each session is consisted of theoretical lecture, mindfulness practices, sharing common difficulties and coping way during mindfulness practices and homework assignment in the form of video or audio. The Mindfulness practices embedded in the intervention include mindful breathing, mindful body scan, mindful dealing with thoughts and emotions, mindful meditation, mindful movement, and daily life mindfulness. In the intervention, the participants will also receive sleep hygiene education.Participants in the Intervention Group will receive the MLWI Intervention after follow the WeChat mini-program.

'Mindful Living With Insomnia (MLWI)' Intervention via WeChat mini-program

The CBT-I involves 12 sessions over 6 weeks course, 2 sessions a week and 0.5 hours per session. Two new sessions of online lessons will be updated weekly in the 6 weeks. Each session is consisted of theoretical lecture, cognitive or behavioral regulation techniques, sharing common difficulties and coping way during mindfulness practices and homework assignment in the form of video or audio.Participants in the Control Group will receive CBT-I after follow the WeChat mini-program.

'Cognitive Behavioral Therapy for insomnia (CBT-I)'via WeChat mini-program

Eligibility Criteria

Age18 Years - 59 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 18 and 59 years old
  • Being able to read and write Chinese
  • PSQI exceeding 5 at screening
  • Being able to access online services
  • Willing to participate in the study

You may not qualify if:

  • Unable to communicate
  • With somatic disorders
  • With mental disorders except for insomnia disorder
  • Being treated with pharmacotherapy
  • Significant current mindfulness practices (\>15 minutes/ day)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Pan C, Tie B, Yuwen W, Su X, Deng Y, Ma X, Wu Y, Liao Y, Kong L, Zhang Y, Li Z, Pan Q, Tang Q. 'Mindfulness Living with Insomnia': an mHealth intervention for individuals with insomnia in China: a study protocol of a randomised controlled trial. BMJ Open. 2022 Feb 15;12(2):e053501. doi: 10.1136/bmjopen-2021-053501.

MeSH Terms

Conditions

Sleep Initiation and Maintenance Disorders

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Sleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Chen Pan, Dr

    The Third Xiangya Hospital,Central South University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 7, 2021

First Posted

March 19, 2021

Study Start

January 1, 2022

Primary Completion

December 31, 2022

Study Completion

March 31, 2023

Last Updated

March 19, 2021

Record last verified: 2021-03

Data Sharing

IPD Sharing
Will not share