Assessment of the 90-day Mortality Risk Score After VATS Lobectomy
1 other identifier
observational
2,209
0 countries
N/A
Brief Summary
A five classes (A-E) aggregate risk score predicting 90-day mortality after video-assisted thoracoscopic lobectomy for lung cancer, including as independent factors male sex (3 points), carbon monoxide lung diffusion capacity \<60% (1 point) and operative time \>150 minutes (1 point), has been recently published. This study aims to assess the effectiveness and reliability of this risk model in a large, independent cohort of patients, in order to confirm its generalizability.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2014
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 27, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
November 27, 2018
CompletedFirst Submitted
Initial submission to the registry
March 12, 2021
CompletedFirst Posted
Study publicly available on registry
March 16, 2021
CompletedMarch 22, 2021
March 1, 2021
4.9 years
March 12, 2021
March 17, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
90-day postoperative mortality
Alive/Death (cause of death)
90 day post surgical procedure
Interventions
VATS lobectomy
Eligibility Criteria
All patients were selected from the Italian VATS Group registry (a database containing prospectively collected data on VATS anatomical lung resection performed in 58 certified thoracic surgery centers from January 1st 2014). The VATS Group database was awarded by the European Society of Thoracic Surgeons in the 2017
You may qualify if:
- \- Patients undergoing VATS lobectomy for non-small cell lung cancer
You may not qualify if:
- Incomplete data for risk score calculation
- Tumor size \>5 cm
- Follow-up \<3 months
- Patients undergoing neoadjuvant treatment
- Patients undergoing extended resection
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Brunelli A, Dinesh P, Woodcock-Shaw J, Littlechild D, Pompili C. Ninety-Day Mortality After Video-Assisted Thoracoscopic Lobectomy: Incidence and Risk Factors. Ann Thorac Surg. 2017 Sep;104(3):1020-1026. doi: 10.1016/j.athoracsur.2017.02.083. Epub 2017 Jun 1.
PMID: 28577845BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Andrea Imperatori, MD
Università degli Studi dell'Insubria
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator - Clinician at Center for Thoracic Surgery - School of Medicine and Surgery - University of Insubria - Varese
Study Record Dates
First Submitted
March 12, 2021
First Posted
March 16, 2021
Study Start
January 1, 2014
Primary Completion
November 27, 2018
Study Completion
November 27, 2018
Last Updated
March 22, 2021
Record last verified: 2021-03
Data Sharing
- IPD Sharing
- Will not share