Observational Study of Correlation Between Recurrent Basal Cell Carcinoma and Localisation

NCT04795297 | Completed

• 1 other identifier: RECHMPL21_0156
• Study Type: observational
• Target: 804
• Locations: 1 country
• Sites: 1

Brief Summary

.During one year all the resected basal cell carcinomas (BCC) analyzed in Montpellier University Hospital Anatomopathology unit were included in this study. Localisation and histological characteristics were collected. All the recurrences of BCC were searched from the medical records (or histopathology request form). From 804 BCC, 48 were recurrent BCC with or without complete first resection. Patients with recurrent BCC were contacted to obtain agreement and more informations about the first resection and some clinical informations like sun exposure and phototype. The statistical analysis focused on the localisation of recurrent BCC (with a complete first resection) compared to localisations of primary BCC in this population. The goal was to identified localisations with an increased risk of recurrences.

Conditions

Basal Cell Carcinoma

Keywords

Resection of BCC (Basal Cell Carcinoma); Recurrence of BCC (Basal Cell Carcinoma); Localisation

Outcome Measures

Primary Outcomes (1)

• - Determined For each localisation the number of primary and recurrent BCC and analysis of localisation with higher risk of BCC

  \- Determined For each localisation the number of primary and recurrent BCC and analysis of localisation with higher risk of BCC

  1 day

Secondary Outcomes (3)

• Analysis of correlation between localisation and histology characteristics

  1 day

• Analysis of correlation between histological type and recurrence risk

  1 day

• Analysis if there is a difference between first resection histological type and the recurrent histological type

  1 day

Study Arms (2)

recurrent BCC

recurrent BCC

resected BCC

resected BCC

Eligibility Criteria

• Age: 16 Years - 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Cohort : All the resected BCC during one year in Montpellier University Hospital and Millau Hospital (both analyzed in anatomopathology unit in Montpellier University Hospital). Cases : All the cases of recurrent BCC, found after research in medical records or histopathology request form.

You may qualify if:

• \- Patients with resected BCC

You may not qualify if:

• Biopsies of BCC,
• revised surgery of incomplete resection.
• Cases :
• Recurrent BCC with complete first resection
• \- Recurrent BCC with incomplete first resection, Patients with Gorlin syndrome (a genetic disease that increase risk of BCC)

Sponsors & Collaborators

• University Hospital, Montpellier: lead

Study Sites (1)

Uhmontpellier

Montpellier, 34295, France

Location

MeSH Terms

Conditions

Carcinoma, Basal Cell

Condition Hierarchy (Ancestors)

Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms; Neoplasms, Basal Cell

Study Officials

• Sophie Pons, Resident

  University Hospital, Montpellier

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 10, 2021
• First Posted: March 12, 2021
• Study Start: February 1, 2020
• Primary Completion: February 1, 2021
• Study Completion: February 20, 2021
• Last Updated: March 12, 2021

Record last verified: 2021-03

Locations

FR (1)