NCT04792164

Brief Summary

A hernia occurs when an organ 'like intestines' or fatty tissue protrude through a weak point in muscle or connective tissue and one of the most common types of hernia is inguinal. Inguinal hernia defined as a bulge in the inguinal region or scrotum, may be accompanied by dull or burning pain, which worsens by exercise or cough. There are 2 types of inguinal hernia: direct and indirect. Direct inguinal hernia occurs because of a defect or weakness in the transversalis fascia area of the Hesselbach triangle. On the other hand, the indirect inguinal hernia which is the most common inguinal hernia follows the tract of inguinal canal and result from a persistent processus vaginalis. Immediate pain after inguinal herniorrhaphy delays the ambulation which leads to delay in the hospital discharge. Besides that, is the chronic pain that affect 50% of patients which is an important issue that needs to be dealt with. Our aim of this study, is to compare between postoperative period in the patients who received US guided nerve block and in patients who received infiltration only before open inguinal hernia repair, and to show that pre-emptive local anaesthesia will result in better pain control, less postoperative complication, earlier mobilisation, earlier recovery and less analgesia consumption by patients.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
136

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Dec 2021

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 9, 2021

Completed
29 days until next milestone

First Posted

Study publicly available on registry

March 10, 2021

Completed
9 months until next milestone

Study Start

First participant enrolled

December 1, 2021

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 29, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 29, 2023

Completed
Last Updated

November 2, 2021

Status Verified

October 1, 2021

Enrollment Period

1.1 years

First QC Date

February 9, 2021

Last Update Submit

October 31, 2021

Conditions

Outcome Measures

Primary Outcomes (20)

  • Pain Scale (from 1 to 10) 1 is the minimum and 10 the maximum pain severity.

    Assessment of pain scale post operative, lower score mean a better outcome.

    Day 1 postoperative.

  • Pain Scale (from 1 to 10) 1 is the minimum and 10 the maximum pain severity.

    Assessment of pain scale post operative, lower score mean a better outcome.

    Day 2 postoperative.

  • Pain Scale (from 1 to 10) 1 is the minimum and 10 the maximum pain severity.

    Assessment of pain scale post operative, lower score mean a better outcome.

    Day 3 postoperative.

  • Pain Scale (from 1 to 10) 1 is the minimum and 10 the maximum pain severity.

    Assessment of pain scale post operative, lower score mean a better outcome.

    Day 4 postoperative.

  • Pain Scale (from 1 to 10) 1 is the minimum and 10 the maximum pain severity.

    Assessment of pain scale post operative, lower score mean a better outcome.

    Day 30 postoperative.

  • Pain Scale (from 1 to 10) 1 is the minimum and 10 the maximum pain severity.

    Assessment of pain scale post operative, lower score mean a better outcome.

    3 month postoperative for chronic pain.

  • Pain Scale (from 1 to 10) 1 is the minimum and 10 the maximum pain severity.

    Assessment of pain scale post operative, lower score mean a better outcome.

    6 month postoperative for chronic pain.

  • Assessment of early mobilisation.

    When the patient started to mobilise? assessed by monitoring the patients postoperative and record when he started to mobilise.

    Day 1 postoperative period.

  • Assessment of early mobilisation.

    When the patient started to mobilise? assessed by monitoring the patients postoperative and record when he started to mobilise.

    Day 2 postoperative period.

  • Assessment of early mobilisation.

    When the patient started to mobilise? assessed by monitoring the patients postoperative and record when he started to mobilise.

    Day 3 postoperative period.

  • Retain to driving (how many days between surgery and patient back to dive)

    When the patient back to drive his car? assessed by monitoring the patients postoperative and record when he started to drive the car again.

    Postoperative period up to 8 weeks.

  • Retain to work (how many days between surgery and patient back to his work)

    When the patient back to his work or usual activity? assessed by monitoring the patients postoperative and record when he started to work again.

    Postoperative period up to 8 weeks.

  • Length of hospital stay (in days).

    Length of hospital stay post open inguinal hernia repair ( how many days patient spend in the hospital postoperative).

    immediately after the surgery until patient discharged.

  • Frequency of analgesia consumption postoperative.

    Analgesia consumption by patient postoperative (How frequent patient taking analgesia postoperative).

    Day 1 postoperative.

  • Frequency of analgesia consumption postoperative.

    Analgesia consumption by patient postoperative (How frequent patient taking analgesia postoperative).

    Day 2 postoperative.

  • Frequency of analgesia consumption postoperative.

    Analgesia consumption by patient postoperative (How frequent patient taking analgesia postoperative).

    Day 3 postoperative.

  • Frequency of analgesia consumption postoperative.

    Analgesia consumption by patient postoperative (How frequent patient taking analgesia postoperative).

    Day 4 postoperative.

  • Frequency of analgesia consumption postoperative.

    Analgesia consumption by patient postoperative (How frequent patient taking analgesia postoperative).

    Day 5 postoperative.

  • Frequency of analgesia consumption postoperative.

    Analgesia consumption by patient postoperative (How frequent patient taking analgesia postoperative).

    Day 6 postoperative.

  • Frequency of analgesia consumption postoperative.

    Analgesia consumption by patient postoperative (How frequent patient taking analgesia postoperative).

    Day 7 postoperative.

Study Arms (2)

The experimental group will receive US guided nerve block

EXPERIMENTAL

The experimental group will receive US guided nerve block by lidocaine before open inguinal hernia repair.

Procedure: Ultra sound guided nerve block

The control group will receive usual infiltration

OTHER

The control group will receive usual infiltration by lidocaine before open inguinal hernia repair.

Procedure: Usual infiltration

Interventions

Ultra sound guided nerve block by lidocaine before open inguinal hernia repair.

The experimental group will receive US guided nerve block

Usual infiltration by lidocaine before open inguinal hernia repair.

The control group will receive usual infiltration

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who underwent elective inguinal hernia repair (will consider the hernia size).
  • Age from 18-70. (70 with no other comorbiditeis)
  • Their ASA score 1,2 or 3 (American Society of Anesthesia)
  • General Anesthesia.
  • Open inguinal hernia repair.

You may not qualify if:

  • All emergency inguinal hernia repair and recurrent hernia.
  • Children and pregnant women.
  • Patients having regional anesthesia. (Spinal/Local).
  • Laparoscopic inguinal hernia.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Hernia, Inguinal

Condition Hierarchy (Ancestors)

Hernia, AbdominalHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
Double blinded ( Patient and researcher recruiter)
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: 2 Arms Arm1) The experimental group will receive US guided nerve block by Lidocaine+Marcaine concentration (1%+.25%). Arm2) The control group will receive usual infiltration by Lidocaine+Marcaine concentration (1%+.25%).
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor of General Surgery in Imam Abdulrahman bin Faisal University

Study Record Dates

First Submitted

February 9, 2021

First Posted

March 10, 2021

Study Start

December 1, 2021

Primary Completion

December 29, 2022

Study Completion

June 29, 2023

Last Updated

November 2, 2021

Record last verified: 2021-10