NCT03904888

Brief Summary

Evaluate the early postoperative course of patients undergoing laparoscopic inguinal hernia repair with either a conventional or a robot assisted approach and with or without the injection of the trocar wounds with a local anesthetic.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
43mo left

Started Sep 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress65%
Sep 2019Dec 2029

First Submitted

Initial submission to the registry

March 19, 2019

Completed
17 days until next milestone

First Posted

Study publicly available on registry

April 5, 2019

Completed
6 months until next milestone

Study Start

First participant enrolled

September 23, 2019

Completed
9.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2028

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2029

Last Updated

April 11, 2025

Status Verified

April 1, 2025

Enrollment Period

9.2 years

First QC Date

March 19, 2019

Last Update Submit

April 10, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • change in PADSS score

    Time postoperative for the patient to get fit for discharge as determined by a PADSS score (Post Anesthesia Discharge Scoring System) to reach ≥ 9 (10 is maximum). The score will be taken at 2 hourly intervals after surgery (0 hours,2 hours,4 hours,6 hours,8 hours,10 hours,12 hours,14 hours,16 hours,18 hours,20 hours,22 hours,24 hours) up to 24 hours or unitl score is ≥ 9.

    change of Baseline PADSS score up to 24h after surgery or unitl score is ≥ 9

Secondary Outcomes (2)

  • Recurrence rate

    at 12 month

  • Quality of Life assessment: EuraHS Quality of Life questionnaire

    1 month and 12 months post-operatively

Study Arms (4)

l-TAPP without local anesthetics

OTHER

These patients will undergo a laparoscopic surgery without local anaesthetics.

Procedure: l-TAPP

l-TAPP with local anesthetics

OTHER

These patients will undergo a laparoscopic surgery with local anaesthetics.

Procedure: l-TAPPProcedure: local anesthetics

r-TAPP without local anesthetics

OTHER

These patients will undergo a robot-assisted surgery without local anaesthetics.

Procedure: r-TAPP

r-TAPP with local anesthetics

OTHER

These patients will undergo a robot-assisted surgery with local anaesthetics.

Procedure: r-TAPPProcedure: local anesthetics

Interventions

r-TAPPPROCEDURE

Robot-assisted repair

r-TAPP with local anestheticsr-TAPP without local anesthetics
l-TAPPPROCEDURE

Laporoscopic repair

l-TAPP with local anestheticsl-TAPP without local anesthetics

local anesthetics will be administred

l-TAPP with local anestheticsr-TAPP with local anesthetics

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • adult patients presenting with a bilateral inguinal hernia planned for a minimal invasive laparoscopic repair

You may not qualify if:

  • Age below 18 years
  • unilateral groin hernia repair
  • incarcerated hernias
  • open hernia repair
  • no informed consent
  • pregnant women
  • ASA score 4 or more
  • patient included in another study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AZ Maria Middelares

Ghent, 9000, Belgium

RECRUITING

MeSH Terms

Conditions

Hernia, Inguinal

Interventions

Anesthetics, Local

Condition Hierarchy (Ancestors)

Hernia, AbdominalHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

AnestheticsCentral Nervous System DepressantsPhysiological Effects of DrugsPharmacologic ActionsChemical Actions and UsesSensory System AgentsPeripheral Nervous System AgentsCentral Nervous System AgentsTherapeutic Uses

Study Officials

  • Filip Muysoms, MD,PhD

    Algemeen Ziekenhuis Maria Middelares

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Filip Muysoms, MD,PhD

CONTACT

Rita Baumgartner, MSc

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head of Surgery Department

Study Record Dates

First Submitted

March 19, 2019

First Posted

April 5, 2019

Study Start

September 23, 2019

Primary Completion (Estimated)

December 1, 2028

Study Completion (Estimated)

December 1, 2029

Last Updated

April 11, 2025

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will not share

Locations