NCT04761029

Brief Summary

Laparoscopic surgery is frequently used today for abdominal region operations. Laparoscopy has become the preferred treatment for cholecystectomy. Patients undergoing laparoscopic cholecystectomy suffer from acute postoperative pain despite the multimodal analgesic regimen. For this type of surgery, many different field blocks have been used for postoperative analgesia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2018

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2020

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

February 16, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 18, 2021

Completed
Last Updated

February 18, 2021

Status Verified

February 1, 2021

Enrollment Period

2.5 years

First QC Date

February 16, 2021

Last Update Submit

February 16, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • tramadol consumption

    tramadol consumption

    Postoperative 24 hours

Secondary Outcomes (5)

  • Numeric Rating Scale rest

    postoperative 24 hours

  • Numeric Rating Scale during movement

    Postoperative 24 hours

  • additional analgesic use

    Postoperative 24 hours

  • side effect profile

    Postoperative 24 hours

  • sensorial dermatomal block-level

    30 minutes after the block administration and at the postoperative 2nd hour

Study Arms (2)

grup R

ACTIVE COMPARATOR

Unilateral Rhomboid intercostal and subserratus block + intravenous patient-controlled analgesia

Other: RIISDrug: Tramadol

Group P

PLACEBO COMPARATOR

intravenous patient-controlled analgesia

Drug: Tramadol

Interventions

RIISOTHER

unilateral Rhomboid intercostal and subserratus block

grup R

intravenous patient-controlled analgesia (tramadol)

Group Pgrup R

Eligibility Criteria

Age20 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • American Society of Anesthesiology physical status I and II and who gave consent for the blocks were included in the study

You may not qualify if:

  • bleeding disorders,
  • mental incapacity,
  • known allergy to the local anesthetics,
  • body mass index ≥35 kg/m2

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bursa Yuksek Ihtisas Training and Research Hospital

Bursa, 16110, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, Postoperative

Interventions

Tramadol

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Intervention Hierarchy (Ancestors)

CyclohexanolsHexanolsFatty AlcoholsAlcoholsOrganic ChemicalsDimethylaminesMethylaminesAminesLipids

Study Officials

  • Korgün Ökmen, Assoc. PhD.

    Sağlık Bilimleri Üniversitesi Bursa Yüksek İhtisas Eğitim Ve Araştırma Hastanesi

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: retrospective
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator ,Assoc. PhD. M.D.

Study Record Dates

First Submitted

February 16, 2021

First Posted

February 18, 2021

Study Start

January 1, 2018

Primary Completion

July 1, 2020

Study Completion

July 1, 2020

Last Updated

February 18, 2021

Record last verified: 2021-02

Locations