Ultrasound Guided Anterior Quadratus Lumborum Block

NCT03425162 | Completed

• 1 other identifier: BYIEAH
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Percutaneous nephrolithotomy (PNL) is frequently used today for renal stones. percutaneous nephrolithotomy (PNL) procedure has become the treatment of choice for many patients with symptomatic renal stones . Patients undergoing PNL suffer from acute postoperative pain, despite a multimodal analgesic regime. This is a randomised controlled trial efficacy of the anterior Quadratus Lumborum Block (QLB) in terms of analgesic efficacy in patients who undergo percutaneous nephrolithotomy.

Conditions

Postoperative Pain; Ultrasound

Keywords

quadratus lumborum block; pain; ultrasound; percutaneous nephrolithotomy

Outcome Measures

Primary Outcomes (1)

• Visual Analog Scale

  Visual Analog Scale was used for pain.Pain intensity was measured using 0-10 cm visual analogue scale (VAS). (0= no pain, 10=intolerable pain)

  Postoperative 24 hours

Secondary Outcomes (3)

• morphine consumption

  Postoperative 24 hours

• side effect profile

  Postoperative 24 hours

• additional analgesic use

  Postoperative 24 hours

Study Arms (2)

Group A

ACTIVE COMPARATOR

Group A:Ultrasound guided unilateral anterior Quadratus Lumborum block with 20 ml %0.25 bupivacaine+PCA (morphine)

Drug: Morphine Sulfate; Procedure: Group A

Group P

SHAM COMPARATOR

Group P:PCA (morphine)

Drug: Morphine Sulfate; Procedure: Group P

Interventions

Morphine Sulfate DRUG

patient-controlled analgesia (PCA) morphine

Also known as: Morphine

Group A; Group P

Group P PROCEDURE

Group P:patient-controlled analgesia (PCA) morphine

Group P

Group A PROCEDURE

Group A:Ultrasound guided unilateral anterior Quadratus Lumborum block with 20 ml %0.25 Bupivacaine

Also known as: Bupivacaine

Group A

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients who were in the American Society of Anesthesiologists (ASA) I-III class and underwent elective Percutaneous nephrolithotomy

You may not qualify if:

• Previous history of opioid use preoperatively,
• Allergy to local anesthetics,
• The presence of any systemic infection,

Sponsors & Collaborators

• Bursa Yuksek Ihtisas Training and Research Hospital: lead

Study Sites (1)

University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital

Bursa, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, Postoperative; Pain

Interventions

Morphine; Bupivacaine

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Neurologic Manifestations; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Morphine Derivatives; Morphinans; Opiate Alkaloids; Alkaloids; Heterocyclic Compounds; Heterocyclic Compounds, Bridged-Ring; Heterocyclic Compounds, 4 or More Rings; Heterocyclic Compounds, Fused-Ring; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Polycyclic Compounds; Anilides; Amides; Organic Chemicals; Aniline Compounds; Amines

Study Officials

• Korgün Ökmen, M.D

  Bursa Yuksek Ihtisas Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: prospective,randomized,single blind

Study Record Dates

• First Submitted: February 1, 2018
• First Posted: February 7, 2018
• Study Start: February 12, 2018
• Primary Completion: August 18, 2018
• Study Completion: August 18, 2018
• Last Updated: November 21, 2018

Record last verified: 2018-11

Locations

TU (1)