Correlation of Muscle Ultrasound Measures (2D and 3D) With Biphotonic X-ray Absorptiometry in Oldest Old Patients.

NCT04753450 | Completed

• 1 other identifier: RC20_0534
• Study Type: observational
• Target: 62
• Locations: 1 country
• Sites: 1

Brief Summary

The sarcopenia diagnosis is based on the muscle mass and on impaired physical performance. The emerging field of ultrasound assessment of muscle mass in older patients is based on 2d parameters with prediction equations for muscle mass. For the moment, validation of prediction equations in older adults with varying function and health is lacking. The study aims to evaluate correlation of muscle mass between 3D muscle mass measurement and DXA, in order to dispense with the prediction equation.

Conditions

Assessment, Self; Muscle Atrophy; Ultrasound Therapy; Complications; Aging

Outcome Measures

Primary Outcomes (1)

• 3D Correlation between muscle volume measured by 3D ultrasound and standard method : DXA results

  Correlation between muscle volume measured by 3D ultrasound and standard method : DXA results

  1 week

Secondary Outcomes (1)

• 2D correlation between muscle volume measured by 2D ultrasound and standard method : DXA results

  1 week

Interventions

No intervention OTHER

No intervention

Eligibility Criteria

• Age: 75 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Older patients who agrees to participate to the study will undergo 3D ultrasound muscle mass measurement, 2D panoramic mode muscle mass measurement and biphotonic X-ray absorptiometry assessment, the same day. Correlation analysis will be done with the different measurement.

You may qualify if:

• Patients over 75 years old
• Osteoporosis diagnosis confirmed by Dual-energy X-ray Absorptiometry

You may not qualify if:

• Neurocognitive disorders preventing the expression of informed consent
• Patients who cannot undergo an examination in a static position
• Lack of a measurement site (muscle resection or amputation)
• Any state of dehydration or water inflation
• Patient with legal protection measure

Sponsors & Collaborators

• Nantes University Hospital: lead

Study Sites (1)

CHU de Nantes

Nantes, France

Location

MeSH Terms

Conditions

Muscular Atrophy

Condition Hierarchy (Ancestors)

Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 10, 2021
• First Posted: February 15, 2021
• Study Start: March 9, 2021
• Primary Completion: October 19, 2022
• Study Completion: October 19, 2022
• Last Updated: November 14, 2022

Record last verified: 2022-11

Locations

FR (1)