Effect of Acai Berry Consumption on Blood Glucose Levels in Healthy Adults

NCT04748575 | Completed

• 1 other identifier: SMU_ETHICS_2020-21_111
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

Type 2 Diabetes Mellitus is a chronic disease that results in hyperglycaemia. This study aimed to identify whether the anthocyanins contained in acai berries can mitigate postprandial glycaemia in healthy adults when consumed in conjunction with carbohydrate. Study design was double blind randomised crossover with glycaemic levels assessed via capillary blood samples taken at baseline and over a 2 hour post-prandial period.

Conditions

Post-prandial Glycaemia

Keywords

Acai (Euterpe oleracea), acute

Outcome Measures

Primary Outcomes (1)

• Blood glucose

  Finger capillary sample collected by micro cuvette (Glucose 201, HemoCue, UK) and analysed electronically (HemoCue 201+, HemoCue,UK).

  Baseline to 120 minutes after intervention.

Study Arms (2)

Acai smoothie consumption

EXPERIMENTAL

Participants (n=5) in this arm were randomly allocated to consume the acai smoothie at the first intervention. After a 7 day wash-out period, the participants consumed the placebo smoothie.

Dietary Supplement: Acai smoothie

Placebo smoothie consumption

EXPERIMENTAL

Participants (n=5) in this arm were randomly allocated to consume the placebo smoothie at the first intervention. After a 7 day wash-out period, the participants consumed the acai smoothie.

Dietary Supplement: Placebo smoothie

Interventions

Acai smoothie DIETARY_SUPPLEMENT

Smoothie containing 150g acai pulp

Acai smoothie consumption

Placebo smoothie DIETARY_SUPPLEMENT

Control smoothie matched nutritionally (macronutrients) and sensorially to the acai smoothie.

Placebo smoothie consumption

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• BMI of 18.5 - 24.9 kg/m2.

You may not qualify if:

• Known allergy to acai/berries or lactose.
• Pregnant or lactating.
• Alcohol/drug dependency.
• Smoking.
• Currently on an energy-restriction diet or have had a body weight change \>10% in last 2 months.
• Eating disorders.
• Diagnosed with diabetes or another chronic condition.
• Taking chronic medication.
• Allergy to any of materials used in, or an unsurmountable fear of, the finger-prick procedure.

Sponsors & Collaborators

• St Mary's University College: lead

Study Sites (1)

St Marys University

London, TW1 4SX, United Kingdom

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: Smoothies were prepared by the Laboratory Technician and blinded from the participant and investigator. Acai and placebo smoothies were matched nutritionally including for carbohydrate, total sugars, protein, fat and fibre. Additionally, the smoothies were matched for colour, taste and temperature and were served in opaque containers.
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomised double-blind crossover

Study Record Dates

• First Submitted: February 4, 2021
• First Posted: February 10, 2021
• Study Start: November 5, 2020
• Primary Completion: December 29, 2020
• Study Completion: December 29, 2020
• Last Updated: February 10, 2021

Record last verified: 2021-02

Locations

GB (1)