Dialysis Recovery Time: Associated Factors and Its Relation to Quality of Life

NCT04727281 | Completed

• 1 other identifier: Dialysis Recovery Time
• Study Type: interventional
• Target: 210
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to identify factors affecting dialysis recovery time and the relation between dialysis recovery time and quality of life in hemodialysis patients.

Conditions

Dialysis; Complications

Keywords

dialysis, recovery time, fatigue, quality of life

Outcome Measures

Primary Outcomes (1)

• dialysis recovery time

  The time needed for the patient to recover from a dialysis session (in minutes).

  48-72 hours

Secondary Outcomes (2)

• quality of life assessment

  90 days

• nutritional status

  90 days

Study Arms (1)

dialysis patients

EXPERIMENTAL

Patients included in the study will be recruited from the dialysis units in Alexandria University Hospitals.

Other: Quality of life assessment using the Kidney Disease Quality of Life 36 (KDQOL-36) short form and Malnutrition-Inflammation Score

Interventions

Quality of life assessment using the Kidney Disease Quality of Life 36 (KDQOL-36) short form and Malnutrition-Inflammation Score OTHER

Data about nutritional status using the Malnutrition-Inflammation Score, and Quality of life assessment using the Kidney Disease Quality of Life 36 (KDQOL-36) short form. Dialysis related data, The time needed for the patient to recover from a dialysis session (in minutes), Detailed history taking, Thorough physical examination, Laboratory Investigations: • Hemoglobin , Serum sodium and potassium , Serum creatinine and blood urea , Serum phosphorus, serum calcium , Serum PTH level , Serum albumin ,CRP ,Total iron-binding capacity .

dialysis patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• End Stage renal disease patients who have been assigned to regular long-term hemodialysis and perform thrice weekly, four hours HD sessions for more than 90 days.
• Patient's age of 18 years of more. They should be able to read and write, and in a complete mental health.

You may not qualify if:

• Inability to answer the questionnaires because of hearing or reading problems, dementia, actual instability of clinical conditions requiring hospitalization, liver failure, and active cancer.
• Patients who experience a decline in the level of consciousness during the HD session.

Sponsors & Collaborators

• Alexandria University: lead

Study Sites (1)

Faculty of Medicine, Alexandria University

Alexandria, Egypt

Location

Related Publications (6)

• Lindsay RM, Heidenheim PA, Nesrallah G, Garg AX, Suri R; Daily Hemodialysis Study Group London Health Sciences Centre. Minutes to recovery after a hemodialysis session: a simple health-related quality of life question that is reliable, valid, and sensitive to change. Clin J Am Soc Nephrol. 2006 Sep;1(5):952-9. doi: 10.2215/CJN.00040106. Epub 2006 Jul 6.

  PMID: 17699312 BACKGROUND

• Sakkas GK, Karatzaferi C. Hemodialysis fatigue: just "simple" fatigue or a syndrome on its own right? Front Physiol. 2012 Jul 31;3:306. doi: 10.3389/fphys.2012.00306. eCollection 2012. No abstract available.

  PMID: 22934057 BACKGROUND

• Rayner HC, Zepel L, Fuller DS, Morgenstern H, Karaboyas A, Culleton BF, Mapes DL, Lopes AA, Gillespie BW, Hasegawa T, Saran R, Tentori F, Hecking M, Pisoni RL, Robinson BM. Recovery time, quality of life, and mortality in hemodialysis patients: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2014 Jul;64(1):86-94. doi: 10.1053/j.ajkd.2014.01.014. Epub 2014 Feb 14.

  PMID: 24529994 BACKGROUND

• Cohen DE, Lee A, Sibbel S, Benner D, Brunelli SM, Tentori F. Use of the KDQOL-36 for assessment of health-related quality of life among dialysis patients in the United States. BMC Nephrol. 2019 Apr 1;20(1):112. doi: 10.1186/s12882-019-1295-0.

  PMID: 30935377 BACKGROUND

• As'habi A, Tabibi H, Hedayati M, Mahdavi-Mazdeh M, Nozary-Heshmati B. Association of malnutrition-inflammation score, dialysis-malnutrition score and serum albumin with novel risk factors for cardiovascular diseases in hemodialysis patients. Ren Fail. 2015 Feb;37(1):113-6. doi: 10.3109/0886022X.2014.967615. Epub 2014 Oct 8.

  PMID: 25296104 BACKGROUND

• Elsayed MM, Zeid MM, Hamza OMR, Elkholy NM. Dialysis recovery time: associated factors and its association with quality of life of hemodialysis patients. BMC Nephrol. 2022 Sep 1;23(1):298. doi: 10.1186/s12882-022-02926-0.

  PMID: 36050656 DERIVED

MeSH Terms

Conditions

Fatigue

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• montasser M zeid, MD

  Professor of Nephrology & Internal Medicine, Faculty of medicine, Alexandria University

  PRINCIPAL INVESTIGATOR

• mohamed mamdouh el sayed, MD

  Lecturer of Nephrology & Internal Medicine, Faculty of medicine, Alexandria University

  STUDY CHAIR

• osama M Refai, MBBCh

  resident of Nephrology & Internal Medicine, Alexandria University Hospitals

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor & lecturer

Study Record Dates

• First Submitted: January 19, 2021
• First Posted: January 27, 2021
• Study Start: February 1, 2021
• Primary Completion: August 15, 2021
• Study Completion: September 15, 2021
• Last Updated: April 15, 2022

Record last verified: 2022-04

Locations

EG (1)