NCT04719871

Brief Summary

Posterior vitreous detachment is a common event. With optical coherence tomography, the investigators can precisely follow the stage of posterior vitrous detachment. In this study, the investigators investigate if the loss of contact between the vitreous and the fovea is the start of glaucoma progression.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
250

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2020

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2020

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 18, 2021

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 22, 2021

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2021

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2021

Completed
Last Updated

January 26, 2021

Status Verified

January 1, 2021

Enrollment Period

8 months

First QC Date

January 18, 2021

Last Update Submit

January 22, 2021

Conditions

GlaucomaPosterior Vitreous Detachment

Keywords

GlaucomaVitreousProgression

Outcome Measures

Primary Outcomes (1)

  • Glaucoma progression

    glaucoma progression based on analysis of visual fields

    1 day

Secondary Outcomes (1)

  • RNFL decr

    1 day

Study Arms (2)

with posterior vitreous detachment

patient with stage 3 or more of posterior vitreous detachment on optical coherence tomography

without posterior vitreous detachment

patient with stage 2 or less of posterior vitreous detachment on optical coherence tomography

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Retrospective cohort of patient with glaucoma follow in Montpellier hospital

You may qualify if:

  • Patient with glaucoma
  • at least 4 years of follow up
  • at least 6 visual fields
  • at least 4 optical coherence tomographies

You may not qualify if:

  • pars plana vitrectomy
  • others ophtalmological or neurological disease which can modify visual fields

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Uhmontpellier

Montpellier, 34295, France

RECRUITING

MeSH Terms

Conditions

GlaucomaVitreous DetachmentDisease Progression

Condition Hierarchy (Ancestors)

Ocular HypertensionEye DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • MAX VILLAIN, PHD

    UH MONTPELLIER

    STUDY DIRECTOR

Central Study Contacts

Salami OSSENI, resident

CONTACT

65075430tunde.osseni@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 18, 2021

First Posted

January 22, 2021

Study Start

October 1, 2020

Primary Completion

June 1, 2021

Study Completion

November 1, 2021

Last Updated

January 26, 2021

Record last verified: 2021-01

Locations

FR(1)