Nasal Breathing and Physical Capacity

NCT04712799 | Unknown Phase 4

• 1 other identifier: SorlandetHF steinsvåg
• Study Type: interventional
• Target: 67
• Locations: 1 country
• Sites: 1

Brief Summary

We know that there is a link between disorders in the upper and lower airways, both epidemiologically, patho-physiologically, and therapeutically. What we know less about is the role for the nose and nasal breathing for physical capacity. That goes both for the ability of the average, healthy persons well as for patients with ie. asthma and COPD to perform daily life activities as well as exercise and for top athletes to perform their maximum oxygen demanding activities. Without this knowledge, we cannot make evidence based decisions about to what extent measures to open the nose medically and/or surgically should be considered to improve physical capacity at any level. The aim of the present project is to expand our knowledge in the field for the best of the ordinary man, patients with airway disorders, and athletes.

Conditions

Nasal Obstruction; Copd

Keywords

nose; lungs; physical capacity

Outcome Measures

Primary Outcomes (1)

• increased walking distance

  3 years

Study Arms (1)

COPD patients

EXPERIMENTAL

Wlaking tests before and afrer 1 spray with oxymetazoline

Drug: Otrivin

Interventions

Otrivin DRUG

oxymetazoline nasal spray

COPD patients

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• COPD-

You may not qualify if:

• Other pulmonary diseases pregnancy

Sponsors & Collaborators

• Sorlandet Hospital HF: lead

Study Sites (1)

Sørlandet Hospital

Kristiansand, Agder, 4604, Norway

RECRUITING

Related Publications (23)

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  PMID: 19823201 RESULT

MeSH Terms

Conditions

Nasal Obstruction; Pulmonary Disease, Chronic Obstructive

Interventions

xylometazoline

Condition Hierarchy (Ancestors)

Nose Diseases; Respiratory Tract Diseases; Airway Obstruction; Respiratory Insufficiency; Respiration Disorders; Otorhinolaryngologic Diseases; Lung Diseases, Obstructive; Lung Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• sverre steinsvåg, MD, PhD

  senior consultant, professor, investigator

  PRINCIPAL INVESTIGATOR

Central Study Contacts

sverre steinsvåg, MD, PhD

CONTACT

95880342; sverre.steinsvag@sshf.no

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 13, 2021
• First Posted: January 15, 2021
• Study Start: January 13, 2021
• Primary Completion: January 13, 2024
• Study Completion: January 13, 2024
• Last Updated: June 27, 2023

Record last verified: 2023-06

Locations

NO (1)