Drug-Related Problems : Focus on Age and Diabetes

NCT04692220 | Completed

• 1 other identifier: RECHMPL20_0667
• Study Type: observational
• Target: 27,000
• Locations: 1 country
• Sites: 1

Brief Summary

Drug-Related Problems (DRP) are a variety of events or circumstances that can interfere with the expected results of a treatment. They may be due to the drug itself, its association with other treatments, its incompatibility with the patient, its misuse... When these situations result in harm, they are referred to as adverse drug events (ADEs). DRP and particularly ADE represent a major public health problem in healthcare institutions because of their impact on morbidity and health costs. DRPs are largely preventable and actions can be set up to detect and correct them. It is in this context that clinical pharmacy has expanded, with the development of new activities to help secure drug management. In our institution, the investigators have implemented several activities in different care services, including

• medication reconciliation,
• an ADE detection. These activities have interesting and encouraging results in terms of impact on the prevention of DRP. However, they can only be carried out on a limited number of patients, depending on the pharmaceutical resources available. The investigators therefore need tools to prioritize our activities on the most at-risk patients. In this study, the investigators seek to identify DRP risk factors and develop DRP risk scores, with the objective to improve the detection and even prevention of DRP. Translated with www.DeepL.com/Translator (free version)

Conditions

Adverse Drug Events

Keywords

Drug-Related Problems; Clinical Pharmacist; Elderly; Diabetes

Outcome Measures

Primary Outcomes (1)

• Variables associated with the presence of an Adverse Drug Events or Drug-Related Problems

  Variables associated with the presence of an Adverse Drug Events or Drug-Related Problems

  1 day

Secondary Outcomes (1)

• Number and type of Adverse Drug Events and Drug-Related Problems

  1 day

Study Arms (2)

Patients with an Adverse Drug Events or Drug-Related Problems

Patients with an Adverse Drug Events or Drug-Related Problems

Other: Detection of Adverse Drug Events or Drug-Related Problems

Patients without an Adverse Drug Events or Drug-Related Problems

Patients without an Adverse Drug Events or Drug-Related Problems

Other: Detection of Adverse Drug Events or Drug-Related Problems

Interventions

Detection of Adverse Drug Events or Drug-Related Problems OTHER

Detection of Adverse Drug Events or Drug-Related Problems

Patients with an Adverse Drug Events or Drug-Related Problems; Patients without an Adverse Drug Events or Drug-Related Problems

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Study population was composed of patient admitted in emergency department or medical units of Montpellier University hospital.

You may qualify if:

• \- Patients aged above 18 years old, admitted to the emergency department or hospital

You may not qualify if:

• Patients presenting acute psychological disturbance
• Patients that did not agree to participate

Sponsors & Collaborators

• University Hospital, Montpellier: lead

Study Sites (1)

Uhmontpellier

Montpellier, 34295, France

Location

MeSH Terms

Conditions

Drug-Related Side Effects and Adverse Reactions; Diabetes Mellitus

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• Cyril BREUKER, PharmD, PhD

  University Hospital, Montpellier

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 28, 2020
• First Posted: December 31, 2020
• Study Start: November 1, 2011
• Primary Completion: March 1, 2021
• Study Completion: March 30, 2021
• Last Updated: October 25, 2021

Record last verified: 2021-10

Locations

FR (1)