Impact of Medication Reconciliation Intervention on the Rate of Preventable Adverse Drug Events (ADEs) and Healthcare Utilization

NCT02805270 | Completed

• 1 other identifier: MREC#715
• Study Type: interventional
• Target: 587
• Locations: 0 countries
• Sites: N/A

Brief Summary

The implementation of a medication reconciliation intervention including: medication reconciliation on admission and discharge, bedside medication counselling and take-home medication list, on the development of adverse drug events within 30 days post discharge as primary outcome. Secondary outcome is the evaluation of its impact on health care resource utilization

Conditions

Adverse Drug Events

Keywords

adverse drug events, preventable, potential, counselling, medication reconciliation

Outcome Measures

Primary Outcomes (2)

• number of patients with a preventable adverse drug event

  30 days

• number of potential adverse drug events

  30 days

Secondary Outcomes (4)

• number of emergency room visits

  30 days

• number of unplanned hospital visits

  30 days

• number of hospital readmissions

  30 days

• number of patients who traveled abroad to seek second medical opinion

  30 days

Study Arms (2)

medication reconciliation intervention

EXPERIMENTAL

medication reconciliation intervention comprises medication reconciliation on admission and discharge, bedside medication counseling and take-home medication list

Other: medication reconciliation intervention

usual care

NO INTERVENTION

Usual care provided by ward pharmacist, nurses and doctors in the ward

Interventions

medication reconciliation intervention OTHER

medication reconciliation intervention comprises medication reconciliation on admission and discharge, bedside medication counseling and take-home medication list

medication reconciliation intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• admitted to one of the two medical wards, male and female medical wards.
• was on at least one medication prior to admission
• spoke Arabic or English and can be (the patient or care giver) interviewed for medication history
• stayed in the hospital for at least 24 hours
• discharged on at least one chronic medication or is at least on one chronic medication even if not prescribed upon discharge

You may not qualify if:

• could not be interviewed due to language barrier, impaired cognition or other reasons and did not have a care giver
• was under specialties other than medical specialties, but was admitted to medical wards because of lack of beds in their respective wards
• was pregnant
• was already included in the study at a previous admission
• left the hospital against medical advice
• with length of stay of \>60 days.

Sponsors & Collaborators

• Sultan Qaboos University: lead

Related Publications (2)

• Schnipper JL, Kirwin JL, Cotugno MC, Wahlstrom SA, Brown BA, Tarvin E, Kachalia A, Horng M, Roy CL, McKean SC, Bates DW. Role of pharmacist counseling in preventing adverse drug events after hospitalization. Arch Intern Med. 2006 Mar 13;166(5):565-71. doi: 10.1001/archinte.166.5.565.

  PMID: 16534045 BACKGROUND

• Kripalani S, Roumie CL, Dalal AK, Cawthon C, Businger A, Eden SK, Shintani A, Sponsler KC, Harris LJ, Theobald C, Huang RL, Scheurer D, Hunt S, Jacobson TA, Rask KJ, Vaccarino V, Gandhi TK, Bates DW, Williams MV, Schnipper JL; PILL-CVD (Pharmacist Intervention for Low Literacy in Cardiovascular Disease) Study Group. Effect of a pharmacist intervention on clinically important medication errors after hospital discharge: a randomized trial. Ann Intern Med. 2012 Jul 3;157(1):1-10. doi: 10.7326/0003-4819-157-1-201207030-00003.

  PMID: 22751755 BACKGROUND

MeSH Terms

Conditions

Drug-Related Side Effects and Adverse Reactions

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders

Study Officials

• Amna Al-Hashar, PhD candidate

  Sultan Qaboos University College of Medicine and Health Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 15, 2016
• First Posted: June 17, 2016
• Study Start: January 1, 2014
• Primary Completion: February 1, 2015
• Study Completion: February 1, 2015
• Last Updated: June 21, 2016

Record last verified: 2016-06

Data Sharing

• IPD Sharing: Will not share