NCT04691973

Brief Summary

The overall aim of the study is to observe the natural pattern of usage and metabolic outcomes in patients with type 2 diabetes who had access to the new digital tool as a stand-alone support in addition to usual care. The tool is based on self-affirmation theory and has large emphasis on self-reflection to enable sustainable lifestyle changes. The changes in HbA1c, reflecting long-term blood glucose, will be evaluated in patients with type 2 diabetes. Patients are compared to controls on usual care not exposed to the tool.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
8mo left

Started Jan 2017

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress94%
Jan 2017Dec 2026

Study Start

First participant enrolled

January 1, 2017

Completed
4 years until next milestone

First Submitted

Initial submission to the registry

December 30, 2020

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 31, 2020

Completed
6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

July 16, 2025

Status Verified

July 1, 2025

Enrollment Period

10 years

First QC Date

December 30, 2020

Last Update Submit

July 13, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change of long-term blood glucose concentration measured as glycated hemoglobin at 3 months

    Intraindividual change of long-term blood glucose concentration measured as glycated hemoglobin (HbA1c) at 3 months relative to baseline compared between participants with access to the tool and on usual care.

    3 months

  • Change of long-term blood glucose concentration measured as glycated hemoglobin at one year

    Intraindividual change of long-term blood glucose concentration measured as glycated hemoglobin (HbA1c) at one year relative to baseline between participants who use the tool as recommended and matched controls on usual care

    One year of the open-label observation period

Secondary Outcomes (15)

  • Change of long-term blood glucose concentration measured as glycated hemoglobin at three years

    Up to three years of the open-label observation period

  • Body weight

    1 year

  • Fat mass

    1 year

  • Muscle mass

    1 year

  • Insulin resistance

    1 year

  • +10 more secondary outcomes

Other Outcomes (1)

  • Change of long-term blood glucose concentration measured as glycated hemoglobin in participants with and without Mild Obesity-related Diabetes, respectively.

    3 months and 1 year

Study Arms (2)

Access to tool

Access to the digital tool. Participants use the tool at their own in addition to usual care and do the different themes that are available. They are recommended to use it at least every other week.

Behavioral: Health and lifestyle tool

No access to tool

Participants are followed by their ordinary healthcare provider and are not exposed to the tool.

Other: Usual care

Interventions

Health and lifestyle tool used online

Access to tool

Usual care at ordinary healthcare provider

No access to tool

Eligibility Criteria

Age35 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Individuals with type 2 diabetes, independent of disease duration or treatment

You may qualify if:

  • Patients with type 2 diabetes at or above 35 years of age
  • HbA1C at 52 mmol/mol or above
  • Diagnosis of diabetes mellitus was based on prior documentation or treatment with anti-hyperglycemic medication
  • written informed consent.

You may not qualify if:

  • type 1 diabetes, MODY or secondary diabetes
  • conditions or treatments that in the judgement of the Investigator could affect the study evaluation
  • connection with the study team, funders, authorities, universities or other public or private bodies in such a way that specific interests in the study outcomes could be suspected.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clinical Research Center

Malmo, 20502, Sweden

Location

Related Publications (1)

  • Dwibedi C, Mellergard E, Gyllensten AC, Nilsson K, Axelsson AS, Backman M, Sahlgren M, Friend SH, Persson S, Franzen S, Abrahamsson B, Carlsson KS, Rosengren AH. Effect of self-managed lifestyle treatment on glycemic control in patients with type 2 diabetes. NPJ Digit Med. 2022 May 11;5(1):60. doi: 10.1038/s41746-022-00606-9.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Interventions

Health

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

Population Characteristics

Study Officials

  • Anders Rosengren, Prof

    Region Skåne

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 30, 2020

First Posted

December 31, 2020

Study Start

January 1, 2017

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

July 16, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will share

Individual participant data that underlie the results will be shared after deidentification.

Time Frame
Data will be available after publication.
Access Criteria
To researchers who provide a methodologically sound proposal in order to achieve the aims of that proposal. Proposals should be directed by email to internetverktyg@gu.se

Locations