NCT04691921

Brief Summary

The investigators aim to understand the variation in pharmacological therapies for the management of severe coronavirus disease 2019 (COVID-19) in India and compare it to the recent available evidence. The ongoing pandemic of COVID-19 has proven to be the greatest medical emergency of recent times. The evidence on the therapeutics has evolved significantly in last few months after initial use of re-purposed drugs. The objective of this study is to understand the current practices in the management of adults severe COVID-19 in India.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,055

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 30, 2020

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 31, 2020

Completed
4 days until next milestone

Study Start

First participant enrolled

January 4, 2021

Completed
14 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 18, 2021

Completed
13 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2021

Completed
Last Updated

February 16, 2021

Status Verified

February 1, 2021

Enrollment Period

14 days

First QC Date

December 30, 2020

Last Update Submit

February 13, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Choice and indication of pharmacological agents for management of Severe COVID-19

    Cross-sectional survey will capture the current choice and indication of different pharmacological agents for management of Severe COVID-19 among participating physicians in India

    two weeks

Interventions

Current clinical practice of participating physicians on choice of pharmacological agents for clinical management of Severe COVID-19

Eligibility Criteria

Age20 Years - 70 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Physicians involved in the clinical management of adult severe COVID-19 patients in India.

You may qualify if:

  • Physicians who are involved in management of adult patients with severe COVID-19 in India

You may not qualify if:

  • Pediatrician Physicians who are not managing severe COVID-19 patients or refused to participate.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Reliance Hospital

Mumbai, Mumbai, Mahrastra, India

Location

Related Publications (2)

  • Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020 Apr 7;323(13):1239-1242. doi: 10.1001/jama.2020.2648. No abstract available.

  • Berlin DA, Gulick RM, Martinez FJ. Severe Covid-19. N Engl J Med. 2020 Dec 17;383(25):2451-2460. doi: 10.1056/NEJMcp2009575. Epub 2020 May 15. No abstract available.

Related Links

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Prashant Nasa, MD EDICM

    NMC Specialty Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Specialist Critical Care Medicine

Study Record Dates

First Submitted

December 30, 2020

First Posted

December 31, 2020

Study Start

January 4, 2021

Primary Completion

January 18, 2021

Study Completion

January 31, 2021

Last Updated

February 16, 2021

Record last verified: 2021-02

Locations