OCTA and Retinal Angiomatous Proliferation
The Role of Quantitative Deep Capillary Plexus in the Pathogenesis of Retinal Angiomatous Proliferation: an Optical Coherence Tomography Angiography Study.
1 other identifier
observational
118
1 country
1
Brief Summary
To investigate, using optical coherence tomography angiography, the retinal vascular features in patients affected by RAP.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Sep 2019
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
December 20, 2020
CompletedFirst Submitted
Initial submission to the registry
December 29, 2020
CompletedFirst Posted
Study publicly available on registry
December 30, 2020
CompletedDecember 30, 2020
December 1, 2020
1.3 years
December 29, 2020
December 29, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
The measurements of retinal vascular network in patients with age-related macular degeneration, using optical coherence tomography angiography, compared to controls
The parameters analyzed by optical coherence tomography angiography were: vessel density of superficial capillary plexus and deep capillary plexus
15 months
Study Arms (3)
Patients with RAP
Patients with previous diagnosis of retinal angiomatous proliferation
Patients with reticular pseudodrusen
Patients with previous diagnosis of reticular pseudodrusen
Control group
Healthy eyes without actual and previous ocular diseases
Interventions
optical coherence tomography aniography is a non-invasive, fast, diagnostic imaging technique that evaluates the retinal vascular network
Eligibility Criteria
The participans were older than 65 years with diagnosis of age-related macular degeneration and in particular retinal angiomatous proliferation and reticular pseudodrusen. They did not present other ophthalmological diseases.
You may qualify if:
- age older than 65 years
- diagnosis of retinal angiomatous proliferation and reticular pseudodrusen
- absence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
- absence of significant lens opacities, low-quality OCT-A images.
You may not qualify if:
- age older than 80 years
- absence of diagnosis of retinal angiomatous proliferation and reticular pseudodrusen
- presence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
- presence of significant lens opacities, low-quality OCT-A images.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Federico II University
Naples, Napoli, 80131, Italy
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Gilda Cennamo
Federico II University
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
December 29, 2020
First Posted
December 30, 2020
Study Start
September 1, 2019
Primary Completion
December 1, 2020
Study Completion
December 20, 2020
Last Updated
December 30, 2020
Record last verified: 2020-12