Rehabilitation Required Due to Clinical Disorders After Severe Covid-19 Infection

NCT04681755 | Unknown

• 1 other identifier: 7725
• Study Type: observational
• Target: 55
• Locations: 1 country
• Sites: 1

Brief Summary

Due to the emergence of an epidemic cluster in Mulhouse, a city located 100 km south of Strasbourg, Alsace was one of the first French regions to be affected by the coronavirus (SARS-CoV-2 or COVID-19). As a result, all hospitals in the region, including both Strasbourg University Hospitals, had to deal with the epidemic wave earlier and more intensely than the rest of France. At the time of writing this article, 6 weeks after the start of the epidemic, we have counted 998 hospital deaths in our region, i.e., an intrahospital mortality rate linked to COVID-19 of 5.3 deaths per 10,000 inhabitants (https://dashboard.covid19.data.gouv.fr/). Currently, our intensive care unit still has a large number of patients hospitalized for COVID-19. Some of these patients have severe damage to one or more organs, and in particular a neurological or respiratory deficit suggesting that they will need post-resuscitation rehabilitation. The primary aim is to assess the neurological disorder after severe SARS-CoV-2 infection and the second is the respiratory impairment evaluation.

Conditions

Covid19

Keywords

Rehabilitation; SARS-CoV-2; COVID-19; Neurological function; Respiratory disorder; Intensive care unit

Outcome Measures

Primary Outcomes (1)

• Retrospective analysis of the neurological disorder after severe SARS-CoV-2 infection

  The files analysed retrospectily from February 24, 2020 to April 15, 2020 will be examined]

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patient with a SARS-CoV-2 infection documented by RT-PCR or with lesions suggestive on chest CT.

You may qualify if:

• Adult patient (≥18 years old)
• Patient hospitalized in surgical intensive care at the New Civil Hospital between February 24 and April 15, 2020.
• Patient with a SARS-CoV-2 infection documented by RT-PCR or with lesions suggestive on chest CT.
• Patient who has given his consent for the use of his data for the purposes of this research

You may not qualify if:

• Patient without documentation of SARS-CoV-2 infection (RT-PCR or chest scanner)
• Patient who expressed his opposition to participating in the study
• Subject under safeguard of justice
• Subject under guardianship or guardianship

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Strasbourg University Hospitals - Anesthesia and surgical resuscitation service

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

COVID-19; Respiration Disorders

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Central Study Contacts

Walid Oulehri, MD

CONTACT

33 3 69 55 12 71; walid.oulehri@chru-strasbourg.fr

Saïd CHAYER, PhD, HDR

CONTACT

33 3 88 11 66 90; said.chayer@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 21, 2020
• First Posted: December 23, 2020
• Study Start: May 19, 2020
• Primary Completion: May 19, 2021
• Study Completion: May 19, 2021
• Last Updated: December 28, 2020

Record last verified: 2020-12

Locations

FR (1)