NCT04679142

Brief Summary

The overall goal of the study is to further characterize the risks and the safety profile of Baclocur® in real life settings, over a 12-month follow-up period.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
975

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2020

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 7, 2020

Completed
15 days until next milestone

First Posted

Study publicly available on registry

December 22, 2020

Completed
Same day until next milestone

Study Start

First participant enrolled

December 22, 2020

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2024

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2025

Completed
Last Updated

January 5, 2021

Status Verified

January 1, 2021

Enrollment Period

3.9 years

First QC Date

December 7, 2020

Last Update Submit

January 4, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Incidence of serious adverse events (SAE)

    To estimate the incidence of serious adverse events (SAE)

    12-month follow-up period

Secondary Outcomes (1)

  • Incidence of all adverse events over the 12-month follow-up

    12-month follow-up period

Study Arms (1)

Adult patients starting a treatment with Baclocur®

Baclofen(Baclocur®) 10mg, 20mg, 30mg, 40mg.

Drug: Baclofen Tablets

Interventions

Enrolled patients will receive treatment and evaluations for their disease as determined by their physicians in accordance with local standard of care. Visits will be scheduled by their physician according to patient-specific needs and national clinical practice.

Also known as: Baclocur®
Adult patients starting a treatment with Baclocur®

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Adult patients starting a treatment with Baclocur®. Patients having already taken Baclocur®/baclofen in the past are not eligible; only treatment-naïve patients are eligible.

You may qualify if:

  • Patient aged 18 or more;
  • Initiating a treatment with Baclocur®;
  • Informed and having agreed to participate in the study;
  • Covered by healthcare insurance.

You may not qualify if:

  • Current participation in a clinical trial;
  • Previous treatment with baclofen/Baclocur®;
  • Patient deprived of liberty by a judicial or administrative decision, or who is under a measure of legal protection (e.g. guardianship or curatorship).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Dijon

Dijon, France

RECRUITING

MeSH Terms

Conditions

Alcoholism

Interventions

Baclofen

Condition Hierarchy (Ancestors)

Alcohol-Related DisordersSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

gamma-Aminobutyric AcidAminobutyratesButyratesAcids, AcyclicCarboxylic AcidsOrganic Chemicals

Study Officials

  • Henri-Jean Aubin, MD, Ph.D

    Hospital Paul Brousse Villejuif France

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 7, 2020

First Posted

December 22, 2020

Study Start

December 22, 2020

Primary Completion

November 1, 2024

Study Completion

November 1, 2025

Last Updated

January 5, 2021

Record last verified: 2021-01

Locations