Molecular Mechanisms of Tooth Eruption
1 other identifier
observational
50
1 country
1
Brief Summary
The main objective is to study the expression of molecules involved in tooth morphogenesis and eruption in healthy patients, and then to compare them with the results in patients with abnormalities of eruption (results obtained via a collection of biological samples of rare diseases already authorized).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Mar 2021
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 14, 2020
CompletedFirst Posted
Study publicly available on registry
December 19, 2020
CompletedStudy Start
First participant enrolled
March 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2023
CompletedMarch 30, 2021
March 1, 2021
Same day
December 14, 2020
March 29, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
Expression and localization of molecules involved in tooth eruption
Tissues are collected at the time of surgery and transferred during the day to the laboratory for analysis
During surgery
Study Arms (1)
Normal tooth eruption
Interventions
Eligibility Criteria
Primary care clinic (Hôpitaux Universitaires de Strasbourg, France)
You may qualify if:
- Patient over 12 years old who has given his consent
- Patient whose legal representatives have given their consent for the use of operating waste destined for incineration
- Patient undergoing oral surgery at the University Hospitals of Strasbourg, at the origin of the production of surgical waste such as teeth and bone fragments
- Patient affiliated to a social security system
You may not qualify if:
- Refusal to participate
- Patient with chronic systemic pathology
- Patient under long-term drug treatment
- Patient presenting a rare pathology with oral manifestation
- Patient with a history of chemotherapy or head and neck radiotherapy
- Non-French speaking patient / inability to give informed information
- Patient under guardianship, curatorship or legal protection
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Les Hôpitaux Universitaires de Strasbourg
Strasbourg, 67091, France
Biospecimen
teeth and bone fragments of the jaw
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 14, 2020
First Posted
December 19, 2020
Study Start
March 1, 2021
Primary Completion
March 1, 2021
Study Completion
January 1, 2023
Last Updated
March 30, 2021
Record last verified: 2021-03