Third Molars Extraction and Periodontal Disease
Correlation Between Upper Third Molars Extraction and Upper Second Molars Periodontal Disease: a Prospective Clinical Observational Study
1 other identifier
observational
126
1 country
1
Brief Summary
The aim of the study is to evaluate the changes in periodontal conditions on the distal aspect of the second maxillary molar after the extraction of the maxillary wisdom tooth. As secondary outcome patient- related and tooth-related factors will be analysed to evaluate their effects on the periodontal varibales during time.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Mar 2024
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 27, 2024
CompletedFirst Submitted
Initial submission to the registry
July 20, 2024
CompletedFirst Posted
Study publicly available on registry
July 25, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 27, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
September 15, 2026
ExpectedJuly 25, 2024
July 1, 2024
2 years
July 20, 2024
July 24, 2024
Conditions
Outcome Measures
Primary Outcomes (2)
Probing Pockeet Depth (PPD)
Distance between the free gingival margin and the apical location of the probe's tip.
Baseline, 1 month, 6 months, 12 months, 24 months
Bone Level (BL)
Distance between the bone crest and the cemento-enamel junction (CEJ)
Baseline, 1 month, 6 months, 12 months, 24 months
Secondary Outcomes (4)
Type of impaction
Baseline
Clinical Attachment Level (CAL)
Baseline, 1 month, 6 months, 12 months, 24 months
Recession (REC)
Baseline, 1 month, 6 months, 12 months, 24 months
Keratinized Tissue (KT)
Baseline, 1 month, 6 months, 12 months, 24 months
Study Arms (2)
Group A with PPD ≤ 3 mm
Group B with PPD ≥ 4 mm
Interventions
Extraction of maxillary third molars
Eligibility Criteria
Hospital population.
You may qualify if:
- Age more than 18 years or older
- Presence of an impacted upper wisdom tooth that need to undergo surgical extraction
- Participants need to be able to sign and understand the informed consent and to follow the study-related procedures.
You may not qualify if:
- People that have compromised general health conditions (ASA 3, 4, 5, 6)
- Patients that assumed antibiotics in the last 6 months
- Pregnant or breastfeeding women
- Patients who suffer from periodontitis stage III and IV
- Presence of a third molar with incomplete root formation is not taken into account for the surgical extraction.
- Smoker patients
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Siena
Siena, Italy/SI, 53100, Italy
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Doctor
Study Record Dates
First Submitted
July 20, 2024
First Posted
July 25, 2024
Study Start
March 27, 2024
Primary Completion
March 27, 2026
Study Completion (Estimated)
September 15, 2026
Last Updated
July 25, 2024
Record last verified: 2024-07