Study Stopped
An six-month follow-up was completed after the treatment
Effect of Cataract Hyperemulsification Surgery on Meibomian Gland Morphology and Function
1 other identifier
observational
N/A
0 countries
N/A
Brief Summary
50 participants at Eye Hospital of Wenzhou Medical University during August, 2017 to July, 2020 will be enrolled in this study. To study the effect of cataract supermammary surgery on the morphology and function of meibomian glands
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started Aug 2017
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2020
CompletedFirst Submitted
Initial submission to the registry
October 4, 2020
CompletedFirst Posted
Study publicly available on registry
December 16, 2020
CompletedDecember 16, 2020
November 1, 2020
2.9 years
October 4, 2020
December 14, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (11)
OSDI scale survey
OSDI scale survey
08/2017 to 07/2020
tear meniscus height（mm）
tear meniscus height（mm）
08/2017 to 07/2020
first tear film rupture time（s）
first tear film rupture time（s）
08/2017 to 07/2020
average tear film rupture time（s）
average tear film rupture time（s）
08/2017 to 07/2020
the range of meibomian gland missing（%）
the range of meibomian gland missing（%）
08/2017 to 07/2020
meibomian gland average diameter (mm)
meibomian gland average diameter (mm)
08/2017 to 07/2020
meibomian gland length (mm)
meibomian gland length (mm)
08/2017 to 07/2020
meibomian gland area (mm^2)
meibomian gland area (mm\^2)
08/2017 to 07/2020
meibomian gland deformation coefficient
meibomian gland deformation coefficient
08/2017 to 07/2020
meibomian gland total proportion of glands (%)
meibomian gland total proportion of glands (%)
08/2017 to 07/2020
meibomian gland imaging value
meibomian gland imaging value
08/2017 to 07/2020
Study Arms (2)
Eyes for cataract surgery
Eyes for cataract surgery
Eyes without cataract surgery
Eyes without cataract surgery
Interventions
Eligibility Criteria
Those patients who undergoing cataract hyperemulsification surgery and previously untreated with xerophthalmia.
You may qualify if:
- Previously untreated patients with xerophthalmia
- Undergoing cataract hyperemulsification surgery
You may not qualify if:
- No history of ocular surgery and trauma
- Any eye diseases except xerophthalmia
- No treated for xerophthalmia before
- Successful completion of follow-ups
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Yune Zhaolead
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Vice president of Eye Hospital of Wenzhou Medical University
Study Record Dates
First Submitted
October 4, 2020
First Posted
December 16, 2020
Study Start
August 1, 2017
Primary Completion
July 1, 2020
Study Completion
September 1, 2020
Last Updated
December 16, 2020
Record last verified: 2020-11